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  1. Total organ failure, multisystem organ failure, multiple organ failure. Causes. Infection, injury, hypermetabolism. Prognosis. Case fatality rate 30–100% depending on the number of organs that failed. Multiple organ dysfunction syndrome ( MODS) is altered organ function in an acutely ill patient requiring medical intervention to achieve ...

    • Infection, injury, hypermetabolism
    • Case fatality rate 30–100% depending on the number of organs that failed
    • Total organ failure, multisystem organ failure, multiple organ failure
  2. Sep 22, 2020 · Multiple organ dysfunction syndrome (MODS) refers to the critical illness characterized by reversible physiological abnormalities with the dysfunction of two or more organs that occurs simultaneously leading to longer stays in the intensive care unit (ICU) and, in severe conditions, results in higher mortality (27%–100%). 1 – 3 MODS is primarily...

    • Mohammad Asim, Farhana Amin, Ayman El-Menyar, Ayman El-Menyar
    • 2020
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  4. Mar 4, 2022 · MODS is defined as the acute and potentially reversible dysfunction of two or more organs triggered by multiple clinical or non-clinical factors. The concept of MODS was first proposed in 1992, which was previously known as multiple organ failure (MOF) ( 3 ).

    • 10.3389/fmed.2022.814381
    • 2022
    • Front Med (Lausanne). 2022; 9: 814381.
    • dendritic cells
  5. Multiple organ system dysfunction is a severe condition that affects two or more organ systems in your body. MODS can affect any organ. But the primary organs include your lungs, heart, kidneys, liver, brain and blood. MODS has many causes, but the general categories include major trauma, severe illness and widespread infection.

  6. Variously known as the multiple organ dysfunction syndrome (MODS), multi-organ failure, multiple systems organ failure, or through some of its more prominent manifestations, as the acute respiratory distress syndrome (ARDS) or disseminated intravascular coagulation (DIC), MODS is as poorly understood as it is prevalent.

    • John C Marshall
    • 2001
  7. Sep 14, 2023 · Multiple organ dysfunction syndrome (MODS), also known as multiorgan failure, is a disorder in which two or more organ systems are not working correctly, usually because of a complex cascade of events initiated by an illness, injury, or severe infection.

  8. Multiple organ failure. Total organ failure. Multiple organ dysfunction syndrome. What does it mean to have organ failure? The term, “organ failure,” can be misleading. It seems to imply that your organ is already expired. But that’s only the end stage. It really means that your organ isn’t up to its full capacity.

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