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  1. Jun 19, 2019 · Epidemiology. Worldwide, neonatal sepsis occurs in about 1 to 50 out of 1,000 live births and accounts for 3 to 30% of infant and child deaths annually [15, 16].In a prospective study performed between 1997 and 1999 at several neonatal centers in South Korea, the incidence rate of neonatal sepsis was 6 per 1,000 live births in those with positive cultures and 30 per 1,000 live births in ...

  2. Jul 5, 2023 · Stratification of Risk of Early-Onset Sepsis in Newborns Greater Than or Equal to 34 Weeks' Gestation. Pediatrics. 133: 30-36. Hornick CP, et al. 2012. Use of the Complete Blood Cell Count in Early-Onset Neonatal Sepsis. Pediatr Infect Dis J. 31: 799-802. Kuzniewicz M. An Evidence Based Approach to Early Onset Sepsis (EOS) and the EOS Calculator.

  3. Apr 21, 2021 · Implementation of neonatal sepsis calculator is associated with a reduction in laboratory tests, antibiotic use, and length of stay related to EOS evaluation. Our data showed that this simple clinical decision support tool could be considered a strategic and objective implementation of managing EOS that can reduce antibiotic usage by more than 27%.

  4. Estimating the probability of neonatal early-onset infection on the basis of maternal risk factors. Pediatrics 2011;128:e1155– e1163. 4. Strunk T, Buchiboyina A, Sharp M, Nathan E, Doherty D, Patole S. Implementation of the Neonatal Sepsis Calculator in an Australian Tertiary Perinatal Centre. Neonatology. 2018;113(4):379-382. doi: 10.1159 ...

  5. The use of the neonatal early-onset sepsis risk calculator, developed by Kaiser Permanente Northern California (CA, USA), is increasing for the management of late preterm and full term newborn babies at risk for early-onset sepsis. The calculator is based on a robust logistic regression model that provides quantitative individualised estimates of early-onset sepsis risk. Low sensitivity for ...

  6. Dec 1, 2018 · The Neonatal Early-Onset Sepsis Risk Calculator 47 is an example of this approach; and ∘ serial physical examination to detect the presence of clinical signs of illness after birth. This approach may begin with a categorical or multivariate assessment to identify newborn infants who are at risk and will be subjected to serial monitoring, or ...

  7. Jan 13, 2022 · The widely used neonatal EOS risk calculator 10 only generates a sepsis risk score for infants ≥34 weeks’ gestation. For those who are well appearing without risk factors for infection, the general recommendation is observation and routine care with vital sign monitoring, which would be routine for any infant at this gestational age.

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