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  1. 1 day ago · Neonatal sepsis is a major cause of childhood mortality. ... vs non-survivor mice in the liver and whole blood. The size of the node ... of end-organ failure in sepsis 18. Of the numerous effects ...

  2. 1 day ago · Sepsis-Associated Liver Injury (SALI) is an independent risk factor for death from sepsis. The aim of this study was to develop an interpretable machine learning model for early prediction of 28-day mortality in patients with SALI. Data from the Medical Information Mart for Intensive Care (MIMIC-IV, v2.2, MIMIC-III, v1.4) were used in this study. The study cohort from MIMIC-IV was randomized ...

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  4. 6 days ago · neonatal sepsis: the first established a cutoff value of 485 pg/mL, with 97.8% sensitivity and 94.1% specificity [11], and the second established a cutoff value of 538 ng/mL, with 79.5% sensitivity and 87.2% specificity [12].

  5. 3 days ago · Background Sepsis is an infection-related systemic inflammatory response that often leads to elevated lactate levels. Monitoring lactate levels during severe sepsis is vital for influencing clinical outcomes. The aim of this study was to assess the association between plasma lactate levels and mortality in children with severe sepsis or septic shock. Methods The current prospective study was ...

  6. 3 days ago · Background Sepsis is one of the main causes of death in newborns worldwide. Vitamin D levels during fetal and neonatal periods have a significant role in the development of the immunological system. The study aims to evaluate the association between vitamin D levels and the risk of early-onset neonatal sepsis in full-term neonates in a developing country. Methods This case–control study was ...

  7. 1 day ago · Methods This was a retrospective case‐control study of neonates born <33 weeks gestational age (GA) who were admitted to a tertiary neonatal intensive care unit, between 2015 and 2018.

  8. 2 days ago · A qSOFA score ≥ 2 is suggestive of sepsis. 12 Sepsis-3 recommends that, for a qSOFA score < 2, the full SOFA score, including laboratory results, should be used. 12. Though the Sepsis-3 tool is more specific for sepsis, using SOFA may be problematic for the emergency clinician.

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