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  1. Dec 31, 2021 · Late-onset sepsis remains a significant cause of morbidity and mortality in neonatal intensive care units (NICU). Its incidence ranges between 10% and 21% in very low birth weight (<1500 g) and between 34% and 41% in extremely low birth weight infants (<1000 g) [ 1 ]. Late-onset sepsis can be diagnosed after 48 h of life [ 2 ], mainly due to ...

  2. Nov 2, 2021 · Neonatal sepsis is still a major cause of morbidity and mortality despite advances in neonatal medicine. 4 Incidence varies from 1 to 4 cases per 1000 live births in high-income countries, but as ...

    • Istemi Han Celik, Morcos Hanna, Fuat Emre Canpolat, Fuat Emre Canpolat, Mohan Pammi
    • 2021
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  4. Jan 12, 2022 · This is known as sepsis-associated liver injury (SALI). • The incidence of sepsis-associated liver injury and its prognostic significance in children is not known.. What is New: • SALI develops in one-third children with sepsis and is associated with a higher pSOFA score. • Children who develop SALI have a higher risk of mortality.

    • Kanwar Saini, Rishi Bolia, Nowneet Kumar Bhat
    • Eur J Pediatr. 2022; 181(4): 1699-1707.
    • 10.1007/s00431-022-04374-2
    • 2022
  5. Sep 29, 2022 · Neonatal sepsis refers to an infection involving the bloodstream in newborn infants less than 28 days old. It remains a leading cause of morbidity and mortality among neonates, especially in middle and lower-income countries [1]. Neonatal sepsis is divided into two groups based on the time of presentation after birth: early-onset sepsis (EOS) and late-onset sepsis (LOS). EOS refers to sepsis ...

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  6. Feb 24, 2024 · In conclusion, current neonatal sepsis management heavily relies on antimicrobial therapy, emphasizing the need for a judicious and evidence-based approach. Ongoing research and the incorporation of innovative strategies are essential to continually improve outcomes for neonates at risk of or affected by sepsis. 11.2.

  7. Nov 5, 2019 · Sepsis, leading to life-threatening organ dysfunction due to a dysregulated host response to infection, 1 is a major contributor to global morbidity and mortality, particularly in early life. 2 In ...

  8. Apr 20, 2017 · defined as a bacterial isolate from culture of blood or CSF obtained from infants in the first 72 h of life who were admitted to neonatal intensive care units, revealed an early-onset neonatal sepsis rate of 6·8 per 1000 admissions from 2003 to 2005 and 6·2 per 1000 admissions from 2006 to 2008.

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