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  1. Aug 1, 2021 · This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever ≥38.0°C. Exclusions are noted. After a commissioned evidence-based review by the Agency for Healthcare Research and Quality, an additional extensive and ongoing review of the literature, and supplemental data from published, peer-reviewed studies provided by active ...

  2. Dec 1, 2018 · Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born preterm, particularly among newborn infants of the lowest gestational age. Currently, most preterm infants with very low birth weight are treated empirically with antibiotics for risk of EOS, often for prolonged periods, in the absence of a culture-confirmed infection. Retrospective studies have revealed that ...

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018
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  4. Feb 23, 2022 · Purpose/Objectives: Neonatal early onset sepsis (EOS) is an invasive bacterial infection of the blood or cerebrospinal fluid occurring in the first week of life. Signs of EOS are nonspecific and therefore difficult to diagnose clinically. EOS is associated with significant morbidity and mortality. In an attempt to avoid missing a diagnosis of EOS, providers may obtain serial complete blood ...

  5. Aug 16, 2022 · Three assessments, presented in Figure 2, namely, One in AAP 2018 American Academy of Pediatrics and two assessments in QH 2020 Queensland Maternity and Neonatal Clinical Guidelines, found a low level of agreement (K = 0.0). No questions in any of the guidelines have a fair degree of agreement.

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