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Broad-spectrum antimicrobial agents (ampicillin and an aminoglycoside)
- The optimal treatment of infants with suspected early-onset sepsis is broad-spectrum antimicrobial agents (ampicillin and an aminoglycoside). Once a pathogen is identified, antimicrobial therapy should be narrowed (unless synergism is needed).
publications.aap.org › pediatrics › articleManagement of Neonates With Suspected or Proven Early-Onset ...
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Aug 1, 2021 · Three algorithms summarize the recommendations for infants 8 to 21 days of age, 22 to 28 days of age, and 29 to 60 days of age. The recommendations in this guideline do not indicate an exclusive course of treatment or serve as a standard of medical care.
Dec 1, 2018 · Tools. Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born preterm, particularly among newborn infants of the lowest gestational age. Currently, most preterm infants with very low birth weight are treated empirically with antibiotics for risk of EOS, often for prolonged periods, in the absence of a culture ...
- Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
- 2018
Jan 1, 2023 · Risk factors for sepsis include birth to mothers with inadequately treated maternal group B Streptococcus colonization, intra-amniotic infection, maternal temperature greater than 100.4°F (>38°C), rupture of membranes greater than 18 hours, and preterm labor.
