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  1. Neonatal sepsis. Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".

  2. Dec 1, 2018 · The incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last 2 decades, primarily because of the implementation of evidence-based intrapartum antimicrobial therapy. However, EOS remains a serious and potentially fatal illness. Laboratory tests alone are neither sensitive nor specific enough to guide EOS management decisions. Maternal and infant clinical ...

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018
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  4. Sep 29, 2022 · Neonatal sepsis refers to an infection involving the bloodstream in newborn infants less than 28 days old. It remains a leading cause of morbidity and mortality among neonates, especially in middle and lower-income countries [1]. Neonatal sepsis is divided into two groups based on the time of presentation after birth: early-onset sepsis (EOS) and late-onset sepsis (LOS). EOS refers to sepsis ...

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  5. Jan 22, 2021 · Random-effects estimator for neonatal sepsis incidence in the overall time frame was 2824 (95% CI 1892 to 4194) cases per 100 000 live births, of which an estimated 17.6% 9 (95% CI 10.3% to 28.6%) died. In the last decade (2009–2018), the incidence was 3930 (95% CI 1937 to 7812) per 100 000 live births based on four studies from LMICs. In the ...

    • Carolin Fleischmann, Felix Reichert, Alessandro Cassini, Rosa Horner, Thomas Harder, Robby Markwart,...
    • 10.1136/archdischild-2020-320217
    • 2021
    • Arch Dis Child. 2021 Aug; 106(8): 745-752.
  6. Dec 1, 2018 · Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born preterm, particularly among newborn infants of the lowest gestational age. Currently, most preterm infants with very low birth weight are treated empirically with antibiotics for risk of EOS, often for prolonged periods, in the absence of a culture-confirmed infection. Retrospective studies have revealed that ...

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018
  7. Oct 4, 2021 · Early neonatal sepsis (ENS) affects a significant number of newborns (NB), and is associated with increasing morbidity and mortality rates in the first week of life. Around the world, it is estimated that the infection is responsible for 27.5% of neonatal deaths, reaching rates as high as 20/1,000 live births in countries with high neonatal ...

  8. Mar 19, 2020 · Pediatric Research - Neonatal sepsis: need for consensus definition, collaboration and core outcomes ... (2017). Article Google Scholar ... Cell 174, 1277–1292 (2018). Article CAS Google Scholar ...

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