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  2. In a randomized controlled trial of 3,003 very low birth weight (VLBW) infants, Heart Rate Characteristics (HRC) monitoring reduced all-cause mortality by 22%, mortality after infection by 40%, reduced length of stay in the NICU after controlling for improved survival, and reduced mortality as well as mortality-or-severe-cerebral-palsy at 18 ...

  3. Jan 22, 2021 · We found a random-effects estimate of 2824 neonatal sepsis cases per 100 000 live births (95% CI 1892 to 4194) in the overall time frame (before 1989–2018), with a 2.6 times higher incidence of EOS (2469/100 000, 95% CI 1424 to 4250) than LOS (946/100 000, 95% CI 544 to 1642) ( figure 3 ).

    • Carolin Fleischmann, Felix Reichert, Alessandro Cassini, Rosa Horner, Thomas Harder, Robby Markwart,...
    • 10.1136/archdischild-2020-320217
    • 2021
    • Arch Dis Child. 2021 Aug; 106(8): 745-752.
  4. Sep 29, 2022 · Despite optimal treatment, neonatal sepsis continues to have high mortality rates and poor outcomes. While the mortality rates have started to decline, the recovery for most infants is prolonged, and there is a risk for neurodevelopmental disabilities.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  5. Oct 1, 2020 · Consider sepsis in infants with an apparent change in mental status, tone, or perfusion as well. Neonatal sepsis can present with subtle signs but can rapidly progress to multisystem organ failure and meningitis, which carry high mortality and morbidity rates.

  6. May 3, 2024 · Español. Key facts. Sepsis is one of the most frequent causes of death worldwide, but there are challenges in collecting reliable data at the population level (1). From data published in 2020, there were 48.9 million cases and 11 million sepsis-related deaths worldwide, representing 20% of all global deaths (2).

  7. Jun 12, 2020 · In connection with this, late-onset neonatal sepsis describes cases diagnosed on 4 th -30 th days of life or cases diagnosed after the first seven days. [ 1, 2] Very late-onset neonatal sepsis, on the other hand, describes sepsis cases diagnosed in infants who are hospitalized in the neonatal intensive care unit from the first 30 days of life un...

  8. The fatality rate is 2 to 4 times higher in LBW infants than in full-term infants. The overall mortality rate of early-onset sepsis is 3 to 40% (that of early-onset GBS infection is 2 to 10%) and of late-onset sepsis is 2 to 20% (that of late-onset GBS is about 2%).

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