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The rationale, effectiveness, and molecular basis of ES and exercise in accelerating axon outgrowth are reviewed. In comparing the effects of ES and exercise in enhancing axon regeneration, increased neural activity, neurotrophins, and androgens are considered common requirements.
Our Neural Regenerative Research Laboratory focuses on improving the function of processed nerves by altering the nerve and microenvironment with surgical angiogenesis, the addition of cellular elements (stem cells and exosomes), and the use of the immune-suppressing medicine tacrolimus.
Sep 15, 2022 · In this article, we provide an overview of nerve regeneration physiology as it relates to peripheral nerve injury, present options for nerve repair, and discuss advances in nerve regeneration, including electrical stimulation, gene therapy, and coaptation techniques .
Nov 10, 2021 · Peripheral nerve injury involves complex molecular, cellular, and genetic events that help in ultimate regeneration of nerve. Some key factors are upregulated and some downregulated in the process of regeneration of nerve to attain almost perfect architecture.
Nov 12, 2013 · To improve regeneration, research is focusing on increasing the speed of axonal growth, preventing neuronal apoptosis and muscle atrophy, and maintaining a supportive environment in the distal...
Oct 26, 2000 · Injury to the adult central nervous system (CNS) is devastating because of the inability of central neurons to regenerate correct axonal and dendritic connections. The consequences of injury are...
Apr 29, 2024 · Regeneration and repair in the nervous system is a process by which damaged tissue undergoes regrowth or renewal, leading to eventual restoration of nervous system function. This process...
