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  2. 5 days ago · Background Sepsis occurs in 12–27% of patients with haematological malignancy within a year of diagnosis. Sepsis mortality has improved in non-cancer patients in the last two decades, but longitudinal trends in patients with haematological malignancy are not well characterised. We aimed to compare outcomes, including temporal changes, in patients with and without a haematological malignancy ...

  3. 23 hours ago · Neutropenia is a medical condition characterized by a low count of neutrophils, which are a type of white blood cell responsible for fighting off infections. Neutropenia can be caused by various factors, both congenital and acquired. Congenital neutropenia is a rare condition that is usually inherited.

  4. 3 days ago · Sepsis. Sepsis is a severe illness characterized by a systemic, whole-body response to infection and is a frequent cause of morbidity and mortality in hospitalized patients. Sepsis is most common in older individuals and infants, and can be difficult to diagnose due to its variable presentation. Because there is no confirmatory diagnostic test ...

  5. 3 days ago · This definition is used uniformly, so that, particularly when entering patients in studies, we are using the same criteria. Neutropenia is currently defined as an absolute neutrophilic count of less than 500/mm 3, or a count of less than 1000/mm 3 with a predicted decline to less than 500/mm 3 in the ensuing 24 to 48 hours. Again, this is to ...

  6. 3 days ago · Quantitative disorders of neutrophils are frequently encountered in clinical practice but seldom present a diagnostic problem. For example, granulocytosis, which is an acute increase in the number of mature and immature granulocytes in circulation, is an anticipated part of the normal response to any infection.

  7. 1 day ago · Read chapter 63 of Harrison's Manual of Medicine, 19e online now, exclusively on AccessMedicine. AccessMedicine is a subscription-based resource from McGraw Hill that features trusted medical content from the best minds in medicine.

  8. 5 days ago · The third international consensus definitions for sepsis and septic shock (sepsis-3). The current definition for Sepsis-3 is as follows: sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to an infection. Sepsis-3 addresses the limitations of previous definitions that focused excessively on ...

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