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Nifurtimox forms a nitro-anion radical metabolite that reacts with nucleic acids of the parasite causing significant breakdown of DNA. Its mechanism is similar to that proposed for the antibacterial action of metronidazole .
- C₁₀H₁₃N₃O₅S
- By mouth
- Lampit
Nifurtimox is an antiprotozoal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of Chagas disease (American Trypanosomiasis), caused by Trypanosoma cruzi, in children who are less than 18 years of age and weigh at least 5.5 lbs. (2.5 kg).
Jun 2, 2023 · LAMPIT (nifurtimox) tablets are yellow round, biconvex tablets, each containing 30 mg or 120 mg of nifurtimox, intended for oral use. The 30 mg tablets are functionally scored on one side and marked with ‘30’ on the other side.
Oct 20, 2016 · Nifurtimox, developed by Bayer, is a nitrofuran antiprotozoal drug used in the treatment of Chagas disease. On August 6 2020, accelerated FDA approval was granted for its use in pediatric patients in response to promising results from phase III clinical trials.
Nifurtimox is used to treat Chagas disease (an infection caused by a parasite) in children from birth to 18 years old who weigh at least 5.5 pounds (2.5 kg). Nifurtimox is in a class of medications called antiprotozoals. It works by killing the organism that can cause Chagas disease.
Feb 1, 2024 · Nifurtimox is used to treat Chagas disease (American Trypanosomiasis) in children. Chagas disease is a potentially life-threatening disease caused by the protozoan parasite, Trypanosoma cruzi, also known as "kissing bug".
Nifurtimox is an antiprotozoal, indicated in pediatric patients (birth to less than 18 years of age and weighing at least 2.5 kg) for the treatment of Chagas disease (American trypanosomiasis), caused by Trypanosoma cruzi.
