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Contents. hide. (Top) Medical uses. Pregnancy and breastfeeding. Side effects. Contraindications. Mechanism of action. Society and culture. Legal status. Names. Research. References. External links. Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness.
- C₁₀H₁₃N₃O₅S
- By mouth
- Lampit
Mar 13, 2023 · Written by Cerner Multum. Uses. Side effects. Warnings. Before taking. Dosage. Interactions. What is nifurtimox? Nifurtimox is used to treat Chagas disease, a condition caused by a parasite. Chagas disease occurs most commonly in Mexico, Central America, and South America. Nifurtimox is for use in children from birth through their 17th year.
Genotoxicity of nifurtimox has been demonstrated in humans, in vitro in several bacterial species and mammalian cell systems, and in vivo in rodents. A study evaluating the cytogenetic effect of nifurtimox in pediatric patients ranging from 7 months to 14 years of age with Chagas disease demonstrated a 13-fold increase in chromosomal aberrations.
Oct 20, 2016 · Nifurtimox, developed by Bayer, is a nitrofuran antiprotozoal drug used in the treatment of Chagas disease. On August 6 2020, accelerated FDA approval was granted for its use in pediatric patients in response to promising results from phase III clinical trials.
Nifurtimox is used to treat Chagas disease (an infection caused by a parasite) in children from birth to 18 years old who weigh at least 5.5 pounds (2.5 kg). Nifurtimox is in a class of medications called antiprotozoals. It works by killing the organism that can cause Chagas disease.
Description. Nifurtimox is a nitrofuran antibiotic. ChEBI. Nifurtimox is an antiprotozoal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of Chagas disease (American Trypanosomiasis), caused by Trypanosoma cruzi, in children who are less than 18 years of age and weigh at least 5.5 lbs. (2.5 kg).
Sep 19, 2023 · Drug Interactions. Pregnancy & Breastfeeding. What Else to Know. Generic Name: nifurtimox. Brand Names: Lampit. Drug Class: Antiprotozoal Agents. What is nifurtimox, and what is it used for? Nifurtimox is a medication used to treat Chagas disease, also known as American trypanosomiasis, in pediatric patients.
