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Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [2][4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [4] . In Chagas disease it is a second-line option to benznidazole. [5] . It is given by mouth. [2]
Nifurtimox, developed by Bayer, is a nitrofuran antiprotozoal drug used in the treatment of Chagas disease. On August 6 2020, accelerated FDA approval was granted for its use in pediatric patients in response to promising results from phase III clinical trials.
Nifurtimox is an antiprotozoal, indicated in pediatric patients (birth to less than 18 years of age and weighing at least 2.5 kg) for the treatment of Chagas disease (American trypanosomiasis), caused by Trypanosoma cruzi.
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Dec 8, 2020 · Nifurtimox is a nitrofuran antiprotozoal. Class: 8:30.92 • Antiprotozoals, Miscellaneous (AHFS primary) Brands: Lampit®.
Jul 18, 2023 · Nifurtimox is a nitrofuran antimicrobial agent used to treat Chagas disease (American trypanosomiasis), a chronic protozoal infection due to Trypanosoma cruzi that can lead to severe disability and death from gastrointestinal and cardiac disease.
Nifurtimox is used to treat Chagas disease (American Trypanosomiasis) in children. Chagas disease is a potentially life-threatening disease caused by the protozoan parasite, Trypanosoma cruzi, also known as "kissing bug".
For oral dosage form (tablets): For the treatment of Chagas disease: Children—Dose is based on body weight and is usually 8 to 20 milligram (mg) per kilogram (kg) of body weight given 3 times a day for 60 days. Weighing 91 kg or more—300 mg (2 ½120 mg tablets) given 3 times a day for 60 days.
