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Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [2] [4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [4] In Chagas disease it is a second-line option to benznidazole. [5] It is given by mouth.
- C₁₀H₁₃N₃O₅S
- By mouth
- Lampit
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- Early Life. Meeting James Barnes. "Even when I had nothing, I had Bucky." ―Steve Rogers. Steve Rogers was born on July 4, 1918, to Sarah and Joseph Rogers in New York City.
- World War II. Rejected for Service. "Look, just give me a chance." "You'll be ineligible on your asthma alone." "Is there anything you can do?" "I'm doing it.
- Captain America. Performing for the USO. "You were meant for more than this, you know." "For the longest time, I dreamed about coming overseas and being on the front lines.
- Fighting HYDRA. Howling Commandos. "That was a difficult winter. A blizzard had trapped half our battalion behind the German line. Steve... Captain Rogers, he fought his way through a HYDRA blockade that had pinned our allies down for months.
Expert tactician and strategist. Master hand-to-hand combatant. Steven Grant Rogers is a fictional character primarily portrayed by Chris Evans in the Marvel Cinematic Universe (MCU) media franchise —based on the Marvel Comics character of the same name —commonly known by his alias, Captain America. Rogers is depicted as a World War II -era ...
- Avengers: Endgame (2019)
Oct 20, 2016 · Nifurtimox. Nifurtimox is an antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). Chagas disease, caused by a parasite known as Trypanosoma cruzi (T.cruzi), is a vector-transmitted disease affecting animals and humans in the Americas. It is commonly known as American Trypanosomiasis. 11.
Jul 18, 2021 · Nifurtimox is a nitrofuran antimicrobial agent used to treat Chagas disease (American trypanosomiasis), a chronic protozoal infection due to Trypanosoma cruzi that can lead to severe disability and death from gastrointestinal and cardiac disease. Nifurtimox is rarely associated with serum aminotransferase elevations during therapy and has not been linked to cases of clinically apparent liver ...
- 2023/07/18
Nifurtimox is used to treat Chagas disease (an infection caused by a parasite) in children from birth to 18 years old who weigh at least 5.5 pounds (2.5 kg). Nifurtimox is in a class of medications called antiprotozoals. It works by killing the organism that can cause Chagas disease.
Genotoxicity of nifurtimox has been demonstrated in humans, in vitro in several bacterial species and mammalian cell systems, and in vivo in rodents. A study evaluating the cytogenetic effect of nifurtimox in pediatric patients ranging from 7 months to 14 years of age with Chagas disease demonstrated a 13-fold increase in chromosomal aberrations.
