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Does nifurtimox treat Chagas disease?
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Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [2] [4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [4] In Chagas disease it is a second-line option to benznidazole. [5] It is given by mouth.
- C₁₀H₁₃N₃O₅S
- By mouth
- Lampit
Oct 20, 2016 · Nifurtimox. Nifurtimox is an antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). Chagas disease, caused by a parasite known as Trypanosoma cruzi (T.cruzi), is a vector-transmitted disease affecting animals and humans in the Americas. It is commonly known as American Trypanosomiasis. 11.
Sep 19, 2023 · Nifurtimox is a medication used to treat Chagas disease, also known as American trypanosomiasis, in pediatric patients. Nifurtimox is under investigation and not yet approved for the treatment of Chagas disease in adults. Common side effects of nifurtimox include vomiting, abdominal pain, decreased appetite, nausea, diarrhea, headache, dizziness, fever (pyrexia), rash, hives (urticaria ...
Nifurtimox comes as a tablet to take by mouth. It is usually taken with food three times a day for 60 days. Take nifurtimox at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nifurtimox exactly as directed.
Nifurtimox is an antiprotozoal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of Chagas disease (American Trypanosomiasis), caused by Trypanosoma cruzi, in children who are less than 18 years of age and weigh at least 5.5 lbs. (2.5 kg). Chagas disease can be an opportunistic infection (OI) of HIV.
Jul 18, 2021 · Nifurtimox is a nitrofuran antimicrobial agent used to treat Chagas disease (American trypanosomiasis), a chronic protozoal infection due to Trypanosoma cruzi that can lead to severe disability and death from gastrointestinal and cardiac disease. Nifurtimox is rarely associated with serum aminotransferase elevations during therapy and has not been linked to cases of clinically apparent liver ...
Aug 24, 2020 · FDA Approves LAMPIT (Nifurtimox) for the Treatment of Chagas Disease in Pediatric Patients. On August 6, 2020, the US Food and Drug Administration (FDA) approved LAMPIT (nifurtimox) for the treatment of Chagas disease (American Trypanosomiasis), caused by Trypanosoma cruzi, in pediatric patients (birth to less than 18 years of age and weighing ...
