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  1. Feb 13, 2024 · Longevity expert Dr. David Sinclair's 2024 anti-aging protocol includes NMN, fish oil, lipoic acid, resveratrol, metformin, spermidine, and more. By Dylan G. Arrazati Published: 7:00 am PST Feb 13, 2024 | Updated: 1:00 p.m. PST Mar 26, 2024

    • Benefits of NMN
    • Benefits of Resveratrol
    • Where to Buy

    NMN, also known as nicotinamide mononucleotide, is a groundbreaking molecule because it is one of the first longevity “substances” to be proven by science to extend lifespan. As we age, our DNA becomes damaged, and our body’s ability to repair that DNA decreases as well. Here’s where NMN is the star – it actually maintains our DNA and helps to repa...

    You’ve likely heard of resveratrol. It’s found in red wine, and one of the reasons drinking a glass at night has health benefits. Resveratrol is in a class of plant micronutrients known as polyphenols. Polyphenols are what plants make to fight disease or survive a drought. One thing researchers like David have concluded is that inflammation is enem...

    David has never mentioned what brand he uses because he uses his lab supply. As mentioned above, avoid Amazon at all costs. Check out this report below that tested 21 brands of NMN on Amazon. Astonishingly, 14 brands were found to contain LESS THAN 1% of the NMN they claimed to have. That’s why we recommend going with Renue by Science. They were th...

    • 11 min
    • Nicotinamide mononucleotide (NMN) Dosage: 1 g per day, in the morning. NMN boosts the production of NAD+, a crucial molecule that fuels a lot of our cellular metabolic reactions needed for survival.
    • Resveratrol. Dosage: 1 g per day, in the morning. Dr. Sinclair’s resveratrol regimen involves a daily dose of 1 g per day in the morning. Resveratrol is a compound naturally found in some plants such as grapes, blueberries, and plums.
    • TMG (trimethyl glycine or betaine) Dosage: 500 mg to 1,000 mg per day. TMG, a glycine amino acid with three methyl groups attached to it, is naturally found inside the body.
    • Metformin. Dosage: 800 mg, in the evening. There are pieces of evidence showing that a drug against type 2 diabetes (T2D) called metformin increases lifespan in a variety of animal models, including mammals.
  2. Jun 23, 2023 · David Sinclair, a pioneering researcher from Harvard Medical School, is neck-deep in the science of anti-aging. His lab’s focus? Zeroing in on potential compounds that hit the brakes on aging. Enter nicotinamide mononucleotide (NMN), an NAD+ precursor that’s turning heads in the longevity arena.

  3. David Sinclair, Harvard University’s noted anti-aging researcher, whose research on resveratrol, NAD+ and sirtuins is world renowned, is also conducting human trials. He is taking NMN himself; he has said his lipid profile has improved dramatically and he feels more energetic and that his blood markers, at nearly 60 years old, are closer to ...

    • Christopher Shade
    • 2020
  4. Nov 3, 2020 · Dr. David Sinclair, professor at Harvard University, has for decades researched aging, more specifically the role of sirtuins in aging. Sirtuins are proteins that repair DNA damage and maintain the epigenome which regulates gene activity (the epigenome determines which genes are switched on or off).

  5. Jan 26, 2022 · 22K. 758K views 2 years ago Podcast Episodes. In this week’s episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat...

    • Jan 26, 2022
    • 760.4K
    • David Sinclair
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