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  1. DMT gained popularity as a drug of abuse in the 1960s and was placed under federal control in schedule I when the Controlled Substances Act was passed in 1971. Today, it is still encountered on the illicit market along with a number of other tryptamine hallucinogens.

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  2. N,N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and animals. It is best known for producing brief and intense psychedelic effects when ingested. Increasing evidence suggests that endogenous DMT plays important roles for a number of processes in the periphery and central nervous system, and may act as a neurotransmitter.

  3. Jul 2, 2017 · N, N -Dimethyltryptamine (DMT) is famous for producing one of the most intense psychedelic experiences possible, catapulting users into a series of vivid, incapacitating hallucinations.

  4. Apr 22, 2023 · Background and Objective. N, N -dimethyltryptamine (DMT) is a psychedelic compound under development for the treatment of major depressive disorder (MDD). This study evaluated the preclinical and clinical pharmacokinetics and metabolism of DMT in healthy subjects.

    • 10.1007/s13318-023-00822-y
    • 2023
  5. Aug 29, 2014 · NN-DMT and bufotenine, the metabolic product of 5-MeO-DMT in mammals, have been detected in animal and human blood, urine, cerebrospinal fluid, brain, intestine and many other tissues suggesting that these compounds may have important biological roles other than their psychotropic and neuromodulatory properties , –.

    • Attila Szabo, Attila Kovacs, Ede Frecska, Eva Rajnavolgyi
    • 10.1371/journal.pone.0106533
    • 2014
    • PLoS One. 2014; 9(8): e106533.
  6. Apr 24, 2024 · 7 min read. What Is DMT? Dimethyltryptamine (DMT) is a compound found in various plants and animals that's used as a mind-altering drug. In large enough doses, DMT can give you a "high" and...

  7. N,N-Dimethyltryptamine ( DMT or N,N-DMT) is a substituted tryptamine that occurs in many plants and animals, including humans, and which is both a derivative and a structural analog of tryptamine. DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen.

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