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A serotonin–norepinephrine–dopamine reuptake inhibitor ( SNDRI ), also known as a triple reuptake inhibitor ( TRI ), is a type of drug that acts as a combined reuptake inhibitor of the monoamine neurotransmitters serotonin, norepinephrine, and dopamine. It does this by concomitantly inhibiting the serotonin transporter (SERT ...
Serotonin–norepinephrine reuptake inhibitors ( SNRIs) are a class of antidepressant medications used to treat major depressive disorder (MDD), anxiety disorders, social phobia, chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms. Off-label uses include treatments for attention-deficit hyperactivity disorder (ADHD ...
Indatraline. Indatraline hydrochloride ( Lu 19-005) is an antidepressive agent and non-selective monoamine transporter inhibitor that blocks the reuptake of dopamine, norepinephrine, and serotonin with similar efficacy to cocaine. [1] This compound may be used to treat cocaine addictions as its effects have a slower onset and a longer duration ...
Serotonin reuptake inhibitor. A serotonin reuptake inhibitor ( SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT). This in turn leads to increased extracellular concentrations of serotonin and, therefore, an ...
Lurasidone. Lurasidone, sold under the brand name Latuda among others, is an antipsychotic medication used to treat schizophrenia and bipolar disorder. [2] It is taken by mouth . Common side effects include sleepiness, movement disorders, nausea, and diarrhea. [2]
Distribution of VMAT2 in the human brain. The solute carrier family 18 member 2 ( SLC18A2) also known as vesicular monoamine transporter 2 ( VMAT2) is a protein that in humans is encoded by the SLC18A2 gene. [5] SLC18A2 is an integral membrane protein that transports monoamines —particularly neurotransmitters such as dopamine, norepinephrine ...
A norepinephrine–dopamine reuptake inhibitor ( NDRI) is a drug used for the treatment of clinical depression, attention deficit hyperactivity disorder (ADHD), narcolepsy, and the management of Parkinson's disease. The drug acts as a reuptake inhibitor for the neurotransmitters norepinephrine and dopamine by blocking the action of the ...
