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1. en.wikipedia.org › wiki › Norepinephrine_transporterNorepinephrine transporter - Wikipedia

   en.wikipedia.org › wiki › Norepinephrine_transporter

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   The norepinephrine transporter ( NET ), also known as noradrenaline transporter ( NAT ), is a protein that in humans is encoded by the solute carrier family 6 member 2 ( SLC6A2) gene. [5] NET is a monoamine transporter and is responsible for the sodium-chloride (Na + /Cl − )-dependent reuptake of extracellular norepinephrine (NE), which is ...

   • Aliases: SLC6A2, NAT1, NET, NET1, SLC6A5, solute carrier family 6 member 2, Norepinephrine transporter, norepinephrine transporter gene

2. en.wikipedia.org › wiki › NorepinephrineNorepinephrine - Wikipedia

   en.wikipedia.org › wiki › Norepinephrine

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   Norepinephrine ( NE ), also called noradrenaline ( NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator. The name "noradrenaline" (from Latin ad, "near", and ren, "kidney") is more commonly used in the United Kingdom, whereas ...

   • Formula: C₈H₁₁NO₃
   • Precursor: dopamine

   • Molar mass: 169.180 g·mol−1

3. People also ask

   What is norepinephrine transporter?

   • Norepinephrine (NE) is the principle chemical messenger employed in central noradrenergic and peripheral sympathetic synapses. The norepinephrine transporter (NET), present on the plasma membrane of noradrenergic neurons, limits the action of NE through reuptake into the cytoplasm.

   The norepinephrine transporter and its regulation - Mandela - 2006

   onlinelibrary.wiley.com/doi/full/10.1111/j.1471-4159.2006.03717.x

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   Which neurotransmitter transports norepinephrine and dopamine?

   • Both the NET and the dopamine transporter (DAT) can transport norepinephrine and dopamine. The reuptake of norepinephrine and dopamine is essential in regulating the concentration of monoamine neurotransmitters in the synaptic cleft. The transporter also helps maintain homeostatic balances of the presynaptic neuron.

   Norepinephrine transporter - Wikipedia

   en.wikipedia.org/wiki/Norepinephrine_transporter

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   Which ion-dependent transporter is responsible for norepinephrine transport in glial cells?

   • The norepinephrine transporter (NET) belongs to the family of sodium-coupled ion-dependent transporters (SLC6). In high density NET occurs in the plasma membranes of noradrenergic neurons and also in glial cells [ 1 ]. It is physiologically responsible for norepinephrine (NE) transport from the synaptic cleft into presynaptic neurons [ 2 ].

   Structure Modeling of the Norepinephrine Transporter - PMC

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7022499/

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   Where is the norepinephrine transporter gene located?

   • The norepinephrine transporter gene, SLC6A2 is located on human chromosome 16 locus 16q12.2. This gene is encoded by 14 exons. Based on the nucleotide and amino acid sequence, the NET transporter consists of 617 amino acids with 12 membrane-spanning domains.

   Norepinephrine transporter - Wikipedia

   en.wikipedia.org/wiki/Norepinephrine_transporter

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4. id.wikipedia.org › wiki › NoradrenalinNoradrenalin - Wikipedia bahasa Indonesia, ensiklopedia bebas

   id.wikipedia.org › wiki › Noradrenalin

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   Noradrenalin. Noradrenalin ( NA ), juga disebut norepinefrin ( NE) adalah kimia organik dalam kelompok katekolamin yang di dalam otak dan tubuh berfungsi sebagai hormon dan neurotransmitter. Nama "noradrenalin," berasal dari bahasa Latin yang berarti "di/bersama ginjal," lebih umum digunakan di Britania Raya; sementara Amerika Serikat, lebih ...

   • Kat. kehamilan: ?
   • Status hukum: ?

   • Kode ATC: ?

5. www.ncbi.nlm.nih.gov › pmc › articlesStructure Modeling of the Norepinephrine Transporter - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 7, 2020 · The norepinephrine transporter (NET) is one of the monoamine transporters. Its X-ray crystal structure has not been obtained yet. Inhibitors of human NET (hNET) play a major role in the treatment of many central and peripheral nervous system diseases. In this study, we focused on the spatial structure of a NET constructed by homology modeling ...

   • Author: Izabella Góral, Kamil Łątka, Marek Bajda
   • DOI: 10.3390/biom10010102

   • Publish Year: 2020
   • Publication: Biomolecules. 2020 Jan; 10(1): 102.

6. www.nature.com › articles › s41467/021/22385-9Structural basis of norepinephrine recognition and ... - Nature

   www.nature.com › articles › s41467/021/22385-9

   Apr 13, 2021 · The Drosophila dopamine transporter (dDAT) is a catecholamine neurotransmitter transporter that resembles the human norepinephrine transporter (hNET). Here the authors report X-ray structures ...

   • Author: Shabareesh Pidathala, Aditya Kumar Mallela, Deepthi Joseph, Aravind Penmatsa

   • Publish Year: 2021

7. onlinelibrary.wiley.com › doi › fullThe norepinephrine transporter and its regulation - Mandela ...

   onlinelibrary.wiley.com › doi › full

   The norepinephrine transporter (NET), present on the plasma membrane of noradrenergic neurons, limits the action of NE through reuptake into the cytoplasm. The NET not only regulates the longevity of NE in the synapse but also plays a very important role in presynaptic and postsynaptic homeostasis ( Axelrod and Kopin 1969 ; Iversen 1971 ; Xu et ...

8. www.nature.com › articles › s41467/021/22385-9Structural basis of norepinephrine recognition and transport ...

   www.nature.com › articles › s41467/021/22385-9

   Dopamine Norepinephrine TM6 Cl Norepinephrine C1 C2 Cβ Cα L-Norepinephrine Cα C1 Cβ C2 Dopamine Cl Na2 Na1 Norepinephrine F325 D121G F319 S426M S422 D46 A428 V120 Y124 F43 A117 3.5 3.8 3.8 2.5 ...