Yahoo Web Search

Search results

1. www.ncbi.nlm.nih.gov › pmc › articlesThe Nucleus Accumbens: Mechanisms of Addiction across Drug ...

   www.ncbi.nlm.nih.gov › pmc › articles

   The nucleus accumbens is a major input structure of the basal ganglia and integrates information from cortical and limbic structures to mediate goal-directed behaviors. Chronic exposure to several classes of drugs of abuse disrupts plasticity in this region, allowing drug-associated cues to engender a pathologic motivation for drug seeking.

   • PMC Free Article

     Both the nucleus accumbens (NAc) and basolateral amygdala...

   • Figure

     The nucleus accumbens is a major input structure of the...

   • Escalation of Cocaine Intake With Extended Access in Rats

     Transition to drug addiction: a negative reinforcement model...

   • MDMA

     INTRODUCTION. Addiction to psychomotor stimulants is a...

   • A Novel Fast Mechanism for GPCR-mediated Signal Transduction—Control of Neurotransmitter Release

     Reliable neuronal communication depends on accurate temporal...

2. www.ncbi.nlm.nih.gov › pmc › articlesMore than Addiction—The Nucleus Accumbens Contribution to ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 27, 2022 · One of the affected structures is nucleus accumbens (NAc). Although its function is commonly known to be associated with brain reward responses and addiction, a growing body of evidence also suggests its role in some mental disorders, such as depression and schizophrenia, as well as neurodegenerative diseases, such as Alzheimer’s, Huntington ...

   • DOI: 10.3390/ijms23052618
   • Published: 2022/03

   • Publication: Int J Mol Sci. 2022 Mar; 23(5): 2618.

3. People also ask

   How does the nucleus accumbens affect drug addiction?

   • The development of drug addiction is associated with functional adaptations within the reward circuitry, within which the nucleus accumbens (NAc) is anatomically positioned as an interface between motivational salience and behavioral output.

   Nucleus accumbens fast-spiking interneurons in motivational and

   www.nature.com/articles/s41380-020-0683-y

   See all results for this question

   Is the nucleus accumbens a comorbidity of depression and addiction?

   • The nucleus accumbens: a common target in the comorbidity of depression and addiction. Front Neural Circuits. 2020;14:37. Myrick H, Anton RF, Li X, Henderson S, Randall PK, Voronin K. Effect of naltrexone and ondansetron on alcohol cue–induced activation of the ventral striatum in alcohol-dependent people. Arch Gen Psychiatry. 2008;65:466–75.

   Deep brain stimulation of the nucleus accumbens in treatment ... - N…

   www.nature.com/articles/s41398-023-02337-1

   See all results for this question

   Does the nucleus accumbens cause depression?

   • Multiple studies have shown that the nucleus accumbens (NAc) is strongly associated with a variety of disorders, especially addiction and depression ( Qi et al., 2011; Gao et al., 2012; Larson et al., 2015 ).

   Frontiers | The Nucleus Accumbens: A Common Target in the Comorbidi…

   www.frontiersin.org/articles/10.3389/fncir.2020.00037/full

   See all results for this question

4. www.ncbi.nlm.nih.gov › books › NBK424849THE NEUROBIOLOGY OF SUBSTANCE USE, MISUSE, AND ADDICTION

   www.ncbi.nlm.nih.gov › books › NBK424849

   The “reward circuitry” of the basal ganglia (i.e., the nucleus accumbens), along with dopamine and naturally occurring opioids, play a key role in the rewarding effects of alcohol and other substances and the ability of stimuli, or cues, associated with that substance use to trigger craving, substance seeking, and use.

   • Published: 2016/11

5. www.nature.com › articles › s41398/023/02337-1Deep brain stimulation of the nucleus accumbens in treatment ...

   www.nature.com › articles › s41398/023/02337-1

   Feb 8, 2023 · Müller U, Sturm V, Voges J, Heinze H-J, Galazky I, Büntjen L, et al. Nucleus accumbens deep brain stimulation for alcohol addiction–safety and clinical long-term results of a pilot trial ...

   • Author: Patrick Bach

6. www.nature.com › articles › s41380/020/0683-yNucleus accumbens fast-spiking interneurons in motivational ...

   www.nature.com › articles › s41380/020/0683-y

   Feb 18, 2020 · These addiction-related emotional and motivational states are thought to be partially mediated by alterations in the functional output of the nucleus accumbens (NAc) induced by repeated exposure ...

   • Author: Terra A Schall, William J Wright, Yan Dong

   • Publish Year: 2021

7. Videos

   • 

     1:58

     youtube.com

     2-Minute Neuroscience: Nucleus Accumbens

     Oct 20, 2016

     147.1K Views

   • 

     18:04

     youtube.com

     Lecture 11 The Neurobiology of Addiction The Reward Pathway

     May 29, 2019

     45.3K Views

   • 

     2:04

     youtube.com

     2-Minute Neuroscience: Reward System

     Feb 13, 2015

     453.7K Views

   View all

8. www.frontiersin.org › articles › 10Frontiers | The Nucleus Accumbens: A Common Target in the ...

   www.frontiersin.org › articles › 10

   • Cached

   The comorbidity of depression and addiction has become a serious public health issue, and the relationship between these two disorders and their potential mechanisms has attracted extensive attention. Numerous studies have suggested that depression and addiction share common mechanisms and anatomical pathways. The nucleus accumbens (NAc) has long been considered a key brain region for ...

9. pubmed.ncbi.nlm.nih.gov › 32694984The Nucleus Accumbens: A Common Target in the Comorbidity of ...

   pubmed.ncbi.nlm.nih.gov › 32694984

   Jun 30, 2020 · The nucleus accumbens (NAc) has long been considered a key brain region for regulating many behaviors, especially those related to depression and addiction. In this review article, we focus on the association between addiction and depression, highlighting the potential mediating role of the NAc in this comorbidity via the regulation of changes ...