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  1. Oct 30, 2023 · The nucleus accumbens receives afferent projections from the prefrontal cortex, amygdaloid complex (via the ventral amygdalofugal pathway), cells of the bed nucleus of the stria terminalis, amygdalofugal fibers that course through the stria terminalis, the hippocampal formation (via the precommissural fornix), thalamus, and from midbrain ...

    • Medical Content
    • 22 min
  2. Oct 18, 2019 · ACC: Anterior cingulate cortex; Amy: amygdala; DH: dorsal horn of the spinal cord; Hab: habenula; Hyp: hypothalamus; Ins: insular cortex; LC: locus coeruleus; NAc: nucleus accumbens; NRM: nucleus raphe magnus; PAG: periaqueductal gray; RVM: rostral ventral medulla; S1: primary somatosensory cortex; Thal: thalamus.

    • Haley N Harris, Yuan B Peng
    • 10.4103/1673-5374.266909
    • 2020
    • Neural Regen Res. 2020 Apr; 15(4): 597-605.
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  4. Cell types: Neurons in the nucleus accumbens are mostly medium spiny neurons (MSNs) containing mainly D1-type (i.e., DRD1 and DRD5) or D2-type (i.e., DRD2, DRD3, and DRD4) dopamine receptors. A subpopulation of MSNs contain both D1-type and D2-type receptors, with approximately 40% of striatal MSNs expressing both DRD1 and DRD2 mRNA.

    • NAc or NAcc
    • Nucleus accumbens shell, Nucleus accumbens core
    • nucleus accumbens septi
  5. Oct 30, 2023 · The hypothalamus is composed of several groups of nuclei which contain neurons that respond to either neural input from widespread regions of the nervous system or non-neural stimuli such as changes in temperature and blood hormone levels.

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    • 33 min
  6. Sep 21, 2023 · The nucleus accumbens (NAcc) is located in the basal forebrain and is a major structure of the ventral striatum, an area of the brain associated with the limbic system, and regulates limbic functions of motivation, affect, and reward.

  7. Dec 28, 2017 · The nucleus accumbens comprises a contingent of neurons specifically expressing the post-synaptic A 2A-receptor (A 2A R) subtype making them excitable by adenosine, its natural agonist endowed...

  8. Jun 6, 2010 · The lateral hypothalamus and the nucleus accumbens shell (AcbSh) are brain regions important for food intake. The AcbSh contains high levels of receptor for melanin-concentrating hormone (MCH), a lateral hypothalamic peptide critical for feeding and metabolism.

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