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  1. Nearly 40 years of research on the function of the nucleus accumbens (NAc) has provided a wealth of information on its contributions to behavior but has also yielded controversies and misconceptions regarding these functions.

  2. Jan 1, 2022 · The nucleus accumbens (NAc), a part of ventral striatum, is mostly involved with reward, motivation, satisfaction, motor function, and learning. NAc itself is made up of two anatomical components, a central core and an outer shell and both has different contributions to the function of nucleus accumbens.

  3. The ventral striatum, including the nucleus accumbens (NAcc), is a major substrate involved in reward ( Marche et al. 2017 ).

  4. The nucleus accumbens has long been considered a key element for the locomotor activation and reinforcing actions of psychostimulants and other drugs of abuse (Di Chiara and North, 1992; Koob, 1992b), and the neuroadaptational changes associated with development of addiction and the reinstatement of drug-seeking behavior after extinction (see ...

  5. Oct 18, 2019 · The nucleus accumbens (NAc) is a subcortical brain structure known primarily for its roles in pleasure, reward, and addiction. Despite less focus on the NAc in pain research, it also plays a large role in the mediation of pain and is effective as a source of analgesia.

  6. Sep 20, 2017 · Definition. The nucleus accumbens is a brain part involved in functions such as motivation, reward or positive behavioral reinforcement. The role of nucleus accumbens is to integrate motivation along with the motor action.

  7. A target of increasing interest is the nucleus accumbens (NAc), which has long been studied as a key brain region mediating a variety of behaviors, including reward and satisfaction.

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