Search results
The nucleus accumbens (NAcc) is a small structure located in the ventral striatum. From a clinical neuroimaging perspective, the NAcc is difficult to image given its size and proximity to cerebral sinuses and pulsating arterioles. Specifically, the NAcc is approximately 1–2 cm 3 in humans relative to a whole-brain volume of 1100 + cm 3 ( Neto ...
Oct 29, 2019 · The nucleus accumbens receives glutaminergic, dopaminergic and histaminergic input fibers from different areas of the brain. The major glutaminergic fibers are received from the prefrontal cortex, basolateral part of the amygdala, midline and intralaminar nuclei of thalamus, and ventral hippocampus.
Nov 7, 2017 · The nucleus accumbens is extremely interconnected with the limbic system of the brain. behavior. It is proposed that the NAc receives mnemonic and emotional cues from nodes in the frontal and temporal lobes of the brain and relays the nervous impulses it receives to particular motor neurons to stimulate a set of responses.
Aug 29, 2018 · The answer lies in the brain circuitry known as the “reward system.”. The regions of the brain comprising the “reward system” use the neurotransmitter dopamine to communicate. Dopamine-producing neurons in the ventral tegmental area (VTA) communicate with neurons in the nucleus accumbens in order to evaluate rewards and motivate us to ...
Dec 28, 2017 · The nucleus accumbens comprises a contingent of neurons specifically expressing the post-synaptic A 2A-receptor (A 2A R) subtype making them excitable by adenosine, its natural agonist endowed ...
In contrast, POMC cell bodies are highly restricted and only detected in three regions of the brain: the arcuate nucleus of the hypothalamus (Arc), nucleus tractus solitarius (NTS, brain stem), and pituitary [anterior lobe (AL) and intermediate lobe (IL)]. However, some mRNA can be detected in other regions by PCR . Neurons from the Arc and NTS ...
The nucleus accumbens is a major input structure of the basal ganglia and integrates information from cortical and limbic structures to mediate goal-directed behaviors. Chronic exposure to several classes of drugs of abuse disrupts plasticity in this region, allowing drug-associated cues to engender a pathologic motivation for drug seeking.
