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1. www.ncbi.nlm.nih.gov › pmc › articlesCerebral malaria: insight into pathogenesis, complications and...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 2, 2017 · Pathogenesis of cerebral malaria is due to damaged vascular endothelium by parasite sequestration, inflammatory cytokine production and vascular leakage, which result in brain hypoxia, as indicated by increased lactate and alanine concentrations.

2. malariajournal.biomedcentral.com › articles › 10Pathophysiology and neurologic sequelae of cerebral malaria

   malariajournal.biomedcentral.com › articles › 10

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   Jul 23, 2020 · Graphical abstract of cerebral malaria pathogenesis. Cerebral malaria pathology manifests itself differently in white matter and gray matter of the brain. Whereas haemorragic punctae are abundant in white matter, they are not obvious in gray matter.

   • Author: Nicoline Schiess, Andres Villabona-Rueda, Karissa E. Cottier, Katherine Huether, James Chipeta, Moni...

   • Publish Year: 2020

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4. www.nature.com › articles › s41582/023/00881-4Pathogenetic mechanisms and treatment targets in cerebral malaria

   www.nature.com › articles › s41582/023/00881-4

   Oct 19, 2023 · Introduction. Malaria is transmitted by the bite of a female Anopheles mosquito infected with the unicellular eukaryote Plasmodium (Fig. 1 ). Among all human-pathogenic Plasmodium species known...

5. journals.plos.org › plospathogens › articleDissecting the mechanisms of pathogenesis in cerebral malaria

   journals.plos.org › plospathogens › article

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   Nov 17, 2022 · Cerebral malaria (CM) is one of the leading causes of death due to malaria. It is characterised by coma, presence of asexual parasites in blood smear, and absence of any other reason that can cause encephalopathy.

6. www.nature.com › articles › nrneurolPathogenesis of cerebral malaria—a step forward | Nature ...

   www.nature.com › articles › nrneurol

   Jul 24, 2012 · Malaria is a devastating disease that is responsible for approximately one million deaths every year. 1 Plasmodium falciparum is the malarial parasite species that causes the most-severe...

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     Malaria Pathophysiology

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     Malaria - Causes, Pathogenesis, Signs and Symptoms, Diagnosis, Treatment and Prevention.

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     Cerebral Malaria: Pathogenesis

     Aug 1, 2021

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8. www.nature.com › articles › pr2010173Cerebral Malaria: Mechanisms of Brain Injury and Strategies ...

   www.nature.com › articles › pr2010173

   The pathogenesis of neurocognitive sequelae is poorly understood: coma develops through multiple mechanisms and there may be several mechanisms of brain injury. It is unclear how an intravascular...