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  1. 1-Phenylcyclohexylamine is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.

    • C12H17N
    • 31.9K
    • 175.27
  2. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay. In addition, we determined the binding affinities of the compounds for PCP acceptor sites …

    • Andrew Thurkauf, Brian De Costa, Shun Ichi Yamaguchi, Mariena V. Mattson, Arthur E. Jacobson, Kenner...
    • 70
    • 1990
  3. Find Similar Structures. Chemical Safety. Laboratory Chemical Safety Summary (LCSS) Datasheet. Molecular Formula. C12H17N. Synonyms. 4-phenylcyclohexanamine. 19992-45-1. 4-Phenylcyclohexylamine.

  4. title = "Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues", abstract = "Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay. In addition, we determined the binding ...

    • Andrew Thurkauf, Brian De Costa, Shun Ichi Yamaguchi, Mariena V. Mattson, Arthur E. Jacobson, Kenner...
    • of Medicinal Chemistry
    • 1990
    • English (US)
  5. An attractive procedure from the standpoint of clandestine synthesis would be the reductive alkylation of PCA with acetone and aluminum amalgam to give the potent analog N-isopropyl phenylcyclohexylamine. The first method using PCA as an intermediate is Scheme IV. This route has received little attention among clandestine chemists, but has ...

  6. Sep 01, 2011 · Synthesis of 1-phenylcyclopentylamine (8a) and 1-phenylcyclohexylamine (8b) 5.2.1. 1-Phenylcyclopentanol (6a) Magnesium turnings (217 mg, 8.93 mmol) in dry THF (5 mL) was placed in ice cold water and iodobenzene (0.73 mL, 6.55 mmol) in dry THF (2 mL) was added dropwise over 10 min.

    • Harichandra D. Tagad, Yoshio Hamada, Jeffrey-Tri Nguyen, Koushi Hidaka, Takashi Hamada, Youhei Sohma...
    • 17
    • 2011
  7. N-Ethyl-1-phenylcyclohexylamine (3) (Procedure B).--A solu- tion of 76 g (0.5 mole) of 25 in 200 ml of Et90 was added to PhLi [prepared from 236 g (1.5 moles) of PhBr and 25 g of I,i ribbon in 800 ml of Et201 at such a rate that a gentle reHux w-as maintained. The mixture was heated and stirred 30 min, then filtered quickly,

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