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1. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo).

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2. www.erowid.org › archive › rhodiumThe Synthesis of Phencyclidine and Other 1 ... - Erowid

   www.erowid.org › archive › rhodium

   The Synthesis of Phencyclidine and Other 1--4rylcyclohexylamines Received Juniiary 10, 1964 Revised Manuscripi Received October 2 $, 1!64 \-arious 1-arylcyclohesylaniiiies were synthesized fur evaliiatioii :ti ceiitral nervous system depressants. The compounds were prepared by several procedures.

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3. People also ask

   Which arylcyclohexylamine was first synthesised?

   • Phencyclidine (PCP) is believed to be the first arylcyclohexylamine with recognized anesthetic properties, but several arylcyclohexylamines were described before PCP in the scientific literature, beginning with PCA (1-phenylcyclohexan-1-amine) the synthesis of which was first published in 1907.

   Arylcyclohexylamine - Wikipedia

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   When was phenyl cyclohexylamine used?

   • PCE was reported in 1953 and PCMo (4- (1-phenyl-cyclohexyl)-morpholine see chart below for figure) in 1954, with PCMo described as a potent sedative. Arylcyclohexylamine anesthetics were intensively investigated at Parke-Davis, beginning with the 1956 studies of PCP and later the related compound ketamine.

   Arylcyclohexylamine - Wikipedia

   en.wikipedia.org/wiki/Arylcyclohexylamine

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   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   What is arylcyclohexylamine?

   • Arylcyclohexylamines, also known as arylcyclohexamines or arylcyclohexanamines, are a chemical class of pharmaceutical, designer, and experimental drugs .

   Arylcyclohexylamine - Wikipedia

   en.wikipedia.org/wiki/Arylcyclohexylamine

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4. en.wikipedia.org › wiki › ArylcyclohexylamineArylcyclohexylamine - Wikipedia

   en.wikipedia.org › wiki › Arylcyclohexylamine

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   Phencyclidine (PCP) is believed to be the first arylcyclohexylamine with recognized anesthetic properties, but several arylcyclohexylamines were described before PCP in the scientific literature, beginning with PCA (1-phenylcyclohexan-1-amine) the synthesis of which was first published in 1907.

   Compound	Aryl Substituent	N Group	Cyclohexyl Ring
   2-HO-PCP	Phenyl	Piperidine	2-Hydroxy
   2-Me-PCP	Phenyl	Piperidine	2-Methyl
   2-MeO-PCP	Phenyl	Piperidine	2-Methoxy
   2-Keto-PCP	Phenyl	Piperidine	2-Keto

   See full list on en.wikipedia.org

5. analyticalsciencejournals.onlinelibrary.wiley.comPreparation and analytical characterization of 1‐(1 ...

   analyticalsciencejournals.onlinelibrary.wiley.com

   Apr 2, 2013 · Preparation and analytical characterization of 1‐ (1‐phenylcyclohexyl)piperidine (PCP) and 1‐ (1‐phenylcyclohexyl)pyrrolidine (PCPy) analogues - Wallach - 2014 - Drug Testing and Analysis - Wiley Online Library.

   • Author: Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt

   • Publish Year: 2014

6. www.semanticscholar.org › paper › THE-SYNTHESIS-OFTHE SYNTHESIS OF PHENCYCLIDINE AND OTHER 1 ...

   www.semanticscholar.org › paper › THE-SYNTHESIS-OF

   A series of phencyclidine homologs was synthesized by reductive cyclization of substituted ω-chlorine-substituted l-N- [l- (p-hydroxybenzyl)cyclohexyl]amides with LiAlH4 by characterized and tested for neurotropic activity. Expand. 1. Synthesis and biological activity of cyclohexylamine derivatives. V. A. Glushkov O. S. P’yankova. +4 authors.

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8. www.semanticscholar.org › paper › Synthesis-andSynthesis and anticonvulsant activity of 1 ... - Semantic Scholar

   www.semanticscholar.org › paper › Synthesis-and

   May 1, 1990 · Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay.

9. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

   webbook.nist.gov › cgi › cbook

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   Formula: C 12 H 17 N. Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N. CAS Registry Number: 1821-36-9. Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file.