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  1. The compounds were prepared by several procedures. 1-( I-Pheiiylcyclohesyl)piperidine, the first compouiid of this type synthesized, was prepared from I-piperidinocyclohexanecarbonitrile by replacement of the cyano group by phenyl using phenylmagnesirim bromide.

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  2. Jan 1, 2016 · Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1).

  3. Apr 2, 2013 · The present study describes the synthesis of three substituted 1-(1-phenylcyclohexyl)piperidines, (3-MeO-, 4-MeO- and 3-Me-PCP) and three substituted 1-(1-phenylcyclohexyl)pyrrolidine analogues (3-MeO-, 4-MeO- and 3-Me-PCPy).

    • Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt
    • 19
    • 2014
    • 02 April 2013
  4. Sep 7, 2023 · [1-Phenylcyclohexyl]piperidine (Phencyclidine, PCP, I) is a noncompetitive antagonist of the NMDA (N-methyl-Daspartate) subcategory of the glutamate receptor that leads to the release and decrease of reabsorbing of monoaminergic neurotransmitters such as dopamine, serotonin, and norepinephrine [1].

  5. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay.

  6. Peptidoglycan is a large polymer that forms a mesh-like scaffold around the bacterial cytoplasmic membrane. Peptidoglycan synthesis is vital at several stages of the bacterial cell cycle: for expansion of the scaffold during cell elongation and for formation of a septum during cell division.

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  8. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay.

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