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2. www.erowid.org › archive › rhodiumThe Synthesis of Phencyclidine and Other 1 ... - Erowid

   www.erowid.org › archive › rhodium

   thesis of 1-phenylcyclohexylamine. The compound prepared by the alternate route (method F) was identi- cal in all respects with the one obtained prepared from Method F aC6"I NCO - CxCeH5 "2 VI phenylcyclohexene. Recently, Cristol, et ul., re- ported the isolation of the amine as its benzoyl deriva- tive via a modified Ritter reaction.

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3. pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine1-Phenylcyclohexylamine | C12H17N | CID 31862 - PubChem

   pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine

   Oct 14, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

4. People also ask

   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   What are arylcyclohexamines?

   • Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1 ).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   Are there any arylcyclohexamine analogues?

   • The only case series of other arylcyclohexamine analogues comes from the Swedish STRIDA project, which reported 59 cases of acute 3- and 4-MeO-PCP toxicity [ 101 ]; 86.4 % were male and the median age was 26 years.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   Does chronic use of arylcyclohexamines affect working memory?

   • The subsequent reduction in dopaminergic activity seen with chronic use of arylcyclohexamines also plays a role in decreased working memory function of the prefrontal cortex [ 226 ].

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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5. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

   webbook.nist.gov › cgi › cbook

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   N-Phenylcyclohexylamine. Formula: C 12 H 17 N. Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. Copy Sheet of paper on top of another sheet. IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N.

6. chem.libretexts.org › Bookshelves › Organic_Chemistry24.6: Synthesis of Amines - Chemistry LibreTexts

   chem.libretexts.org › Bookshelves › Organic_Chemistry

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   Example To synthesize a 1 o or 2 o amine, specific reactions are usually employed. A more efficient method starts with an S N 2 reaction between a 1 o or 2 o alkyl halide and the nucleophilic azide anion (N 3 - ) to produce an alkyl azide.

7. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com › referenceworkentry › 10

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   Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N-ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo). While many were not explored further by their initial investigators, chemists ...

8. chem.libretexts.org › Courses › Athabasca_University24.6 Synthesis of Amines - Chemistry LibreTexts

   chem.libretexts.org › Courses › Athabasca_University

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   Mar 27, 2024 · A specific example of each general class is provided in the diagram below. In the first two, an anionic nitrogen species undergoes an S N 2 reaction with a modestly electrophilic alkyl halide reactant.

9. www.semanticscholar.org › paper › THE-SYNTHESIS-OFTHE SYNTHESIS OF PHENCYCLIDINE AND OTHER 1 ...

   www.semanticscholar.org › paper › THE-SYNTHESIS-OF

   A series of phencyclidine homologs was synthesized by reductive cyclization of substituted ω-chlorine-substituted l-N- [l- (p-hydroxybenzyl)cyclohexyl]amides with LiAlH4 by characterized and tested for neurotropic activity. Expand. 1. Synthesis and biological activity of cyclohexylamine derivatives. V. A. Glushkov O. S. P’yankova. +4 authors.