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Jan 1, 2012 · Alternatively, reaction of the above iminoketals. with methyl fluorosulfonate followed by dry. hydrogen chloride treatment and acid hydrol ysis. gives directly N-methyl-4-piperidones. Analogs of ...
An attractive procedure from the standpoint of clandestine synthesis would be the reductive alkylation of PCA with acetone and aluminum amalgam to give the potent analog N-isopropyl phenylcyclohexylamine. The first method using PCA as an intermediate is Scheme IV. This route has received little attention among clandestine chemists, but has ...
Jan 13, 2023 · Alternatively, the synthesis of 1,2,4,5-tetrasubstituted imidazole derivatives 62 could be achieved through the condensation of benzyl 56, aldehydes 63 and anilines 64 in the presence of ammonium acetate under the solvent-free catalysis of Fe 3 O 4 @SiO 2 /bipyridinium nanocomposite (Fe 3 O 4 @SiO 2 /BNC) (Figure 25). The catalyst was reused ...
Dec 1, 1986 · Phenylcyclohexylamine produced a long-lasting dose-dependent biphasic effect on the efflux of DA in the rat. This response, to one of the major metabolites of phencyclidine, was similar in duration to but less potent than that seen with phencyclidine. Key words: phencyclidine, phenylcyclohexylamine, dopamine, in vivo voltammetry, neostriatum.
Jan 23, 2023 · Acyclic ethers can be prepared using Williamson's synthesis, which involves reacting an alkoxide with a haloalkane. As stated previously, alkoxides are created by reacting an alcohol with metallic sodium or potassium, or a metal hydride, such as sodium hydride (NaH).
Example: Synthesis of PCE (N-ethyl-1-phenylcyclohexylamine): A mixture of 100 g of anhydrous ethylamine and 220 g of cyclohexanone was kept 16 hours, then shaken with solid KOH. The lower oil layer, which comprises the imine ( N-cyclohexylidenethylamine), was then removed by decantation.
Sep 24, 2006 · Synthesis and Properties of Phenyl Cyclohexyl Ferroelectric Liquid Crystals Sun Yongmao Department of Chemistry, Tsinghua University, Beijing, 100084, People's Republic of China Yu Hongping Department of Chemistry, Tsinghua University, Beijing, 100084, People's Republic of China
