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1. analyticalsciencejournals.onlinelibrary.wiley.comPreparation and analytical characterization of...

   analyticalsciencejournals.onlinelibrary.wiley.com

   Apr 2, 2013 · Drug Testing and Analysis is a specialist journal covering sports doping, recreational drugs, pharmaceuticals, toxico-pathology, forensics, and the environment.

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3. link.springer.com › article › 10Synthesis and Analgesic Activity of New Analogs of 1-[1 ...

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   Sep 7, 2023 · Synthesis of Target Compounds (I-IV) Final products were obtained by adding the mixture of 0.05 mol carbonitrile compounds (a-d) in diethyl ether and toluene (1:1) to reagents of phenyl, ortho or para-tolyl magnesium bromide (Grignard reagents, e-g, were obtained from refluxing bromobenzene, 2-bromo toluene or 4-bromo toluene and Mg in dry ether).

4. www.erowid.org › archive › rhodiumPCP analogs via imine intermediates - Erowid

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   PCP analogs via imine intermediates. Reaction Scheme III. Synthesis via imines: This is the best route for synthesis of compounds with mono N-alkyl substituents, such as PCE ( ref. 10 ). An intermediate imine is formed by the reaction of cyclohexanone and the appropriate primary amine. The phenyl group can then be introduced with phenyllithium ...

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   What is arylcyclohexylamine?

   • This compound and its analogs belong to the arylcyclohexylamine family, which has received much investigative attention thanks to a complex spectrum of pharmacological behaviors such as analgesic, anticonvulsant, antianxiety, antidepressant depending on the dose, and the species examined.

   Synthesis and Analgesic Activity of New Analogs of 1-[1-phenylcyclohex…

   link.springer.com/article/10.1007/s11094-023-02934-w

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   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   Can phenyl cyclohexyl and amine rings reduce thermal and chronic chemical pains?

   • It is concluded that compound II with three and compound IV with two changing moieties of PCP on phenyl, cyclohexyl, and amine rings were suitable candidates to reduce acute thermal and chronic chemical pains in Tail immersion and formalin tests, respectively.

   Synthesis and Analgesic Activity of New Analogs of 1-[1-phenylcyclohex…

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   What are arylcyclohexamines?

   • Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1 ).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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6. chemistry.mdma.ch › hiveboard › rhodiumUse of PCA (1-phenylcyclohexylamine) as a precursor

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   An attractive procedure from the standpoint of clandestine synthesis would be the reductive alkylation of PCA with acetone and aluminum amalgam to give the potent analog N-isopropyl phenylcyclohexylamine. The first method using PCA as an intermediate is Scheme IV. This route has received little attention among clandestine chemists, but has ...

7. www.semanticscholar.org › paper › Synthesis-andSynthesis and anticonvulsant activity of 1 ... - Semantic Scholar

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   May 1, 1990 · DOI: 10.1021/JM00167A027 Corpus ID: 11849936; Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues. @article{Thurkauf1990SynthesisAA, title={Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogues.}, author={A. Thurkauf and Brian R. de Costa and Shun-ichi Yamaguchi and Mariena V. Mattson and Arthur E Jacobson and Kenner C. Rice and Michael A. Rogawski ...

8. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N-ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo). While many were not explored further by their initial investigators, chemists ...

9. pubs.acs.org › doi › 101-Phenylcycloalkylamine derivatives. II. Synthesis and ...

   pubs.acs.org › doi › 10

   Synthesis of unlabelled and tritium labelled 4‐isothiocyanato‐1‐(1‐phenylcyclohexyl)piperidine (fourphit), tools for the study of the dopamine reuptake complex.. Journal of Labelled Compounds and Radiopharmaceuticals 1992 , 31 (9) , 671-683.