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1. chem.libretexts.org › Bookshelves › Organic_Chemistry24.6: Synthesis of Amines - Chemistry LibreTexts

   chem.libretexts.org › Bookshelves › Organic_Chemistry

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   Because N-methylbenzylamine has two C-N bonds there are two possible synthesis pathways. Pathway 1 is most likely preferred because it uses the simplest amine starting material, methyl amine. Exercise \(\PageIndex{1}\)

2. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

   webbook.nist.gov › cgi › cbook

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   Feb 6, 2010 · N-Phenylcyclohexylamine. Formula: C 12 H 17 N. Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. Copy Sheet of paper on top of another sheet.

3. pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine1-Phenylcyclohexylamine | C12H17N | CID 31862 - PubChem

   pubchem.ncbi.nlm.nih.gov › 1-phenylcyclohexylamine

   Oct 14, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

4. www.erowid.org › archive › rhodiumThe Synthesis of Phencyclidine and Other 1 ... - Erowid

   www.erowid.org › archive › rhodium

   The reaction of phenylcyclohexene with hydrogen cyanide in strongly acidic media for 2 hr. yielded a fornianiide which on acid hydrolysis produced an amine hydro- chloride whose spectral data and analysis were in agree- ment with structure IIc (Ar = phenyl).

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5. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Jan 1, 2016 · Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1).

6. www.frontiersin.org › journals › chemistryComputational Chemical Synthesis Analysis and Pathway Design

   www.frontiersin.org › journals › chemistry

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   Jun 4, 2018 · LHASA system started the pioneering work of designing semi-empirical reaction modes in computers, with its following rule-based and network-searching work not only expanding the databases, but also building new approaches to indicating reaction rules.

7. People also ask

   How do arylcyclohexamines affect cholinergic pathways?

   • In overdose, the arylcyclohexamines also stimulate sigma receptors [ 155 ], causing an inhibitory effect on cholinergic pathways. It is thought that binding of sigma receptors may play a role in their antidepressant activity [ 156 ].

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   What are arylcyclohexamines?

   • The most well-characterized arylcyclohexamines are phencyclidine ( (1- (1-phencyclohexyl) piperidine; PCP )), ketamine, and, of the novel analogues, methoxetamine. The main effects of this class of agents are nystagmus, hypertension, and tachycardia in a behaviorally disturbed, and possibly violent, patient.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Are arylcyclohexamines dissociative?

   • J Toxicol Clin Toxicol. 1985;23 (7–8):547–56. Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1). They all exhibit dissociative...

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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8. www.researchgate.net › figure › An-overview-towardsAn overview towards the production of cyclohexylamine. (A ...

   www.researchgate.net › figure › An-overview-towards

   Here, a powerful one‐pot Raney Ni‐based catalytic strategy was developed to transform guaiacol into cyclohexylamine using NH3 (7 bar) and H2 (10 bar) in up to 94 % yield. The methodology was ...