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1. chem.libretexts.org › Bookshelves › Organic_Chemistry24.6: Synthesis of Amines - Chemistry LibreTexts

   chem.libretexts.org › Bookshelves › Organic_Chemistry

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   Aldehydes and ketones can be converted into 1 o, 2 o and 3 o amines using reductive amination. The reaction takes place in two parts. The first step is the nucleophiic addition of ammonia, a 1 o amine, or a 2 o amine to a carbonyl group to form an imine ( Section 19-8).

2. analyticalsciencejournals.onlinelibrary.wiley.comPreparation and analytical characterization of 1‐(1 ...

   analyticalsciencejournals.onlinelibrary.wiley.com

   Apr 2, 2013 · The present study describes the synthesis of three substituted 1- (1-phenylcyclohexyl)piperidines, (3-MeO-, 4-MeO- and 3-Me-PCP) and three substituted 1- (1-phenylcyclohexyl)pyrrolidine analogues (3-MeO-, 4-MeO- and 3-Me-PCPy).

   • Author: Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt

   • Publish Year: 2014

3. People also ask

   What was the first arylcyclohexamine?

   • The first arylcyclohexamine to be described was 1- (1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP [ 1 ]. Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1- (1-phenylcyclohexyl)morpholine (PCMo).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com/referenceworkentry/10.1007/978-3-319-20790-2_124-1

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   How many substituted 1 phenylcyclohexyl pyrrolidine analogues are there?

   • The present study describes the synthesis of three substituted 1- (1-phenylcyclohexyl)piperidines, (3-MeO-, 4-MeO- and 3-Me-PCP) and three substituted 1- (1-phenylcyclohexyl)pyrrolidine analogues (3-MeO-, 4-MeO- and 3-Me-PCPy).

   Preparation and analytical characterization of 1‐(1‐phenylcyclohexyl

   analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/dta.1468

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   What are arylcyclohexamines?

   • Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1 ).

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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   Are there any arylcyclohexamine analogues?

   • The only case series of other arylcyclohexamine analogues comes from the Swedish STRIDA project, which reported 59 cases of acute 3- and 4-MeO-PCP toxicity [ 101 ]; 86.4 % were male and the median age was 26 years.

   Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

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4. chemistry.mdma.ch › hiveboard › rhodiumUse of PCA (1-phenylcyclohexylamine) as a precursor

   chemistry.mdma.ch › hiveboard › rhodium

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   An attractive procedure from the standpoint of clandestine synthesis would be the reductive alkylation of PCA with acetone and aluminum amalgam to give the potent analog N-isopropyl phenylcyclohexylamine. The first method using PCA as an intermediate is Scheme IV.

5. webbook.nist.gov › cgi › cbookN-Phenylcyclohexylamine - NIST Chemistry WebBook

   webbook.nist.gov › cgi › cbook

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   Feb 6, 2010 · N-Phenylcyclohexylamine. Formula: C 12 H 17 N. Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. Copy Sheet of paper on top of another sheet. IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N.

6. www.erowid.org › archive › rhodiumThe Synthesis of Phencyclidine and Other 1 ... - Erowid

   www.erowid.org › archive › rhodium

   The Synthesis of Phencyclidine and Other 1--4rylcyclohexylamines Received Juniiary 10, 1964 Revised Manuscripi Received October 2 $, 1!64 \-arious 1-arylcyclohesylaniiiies were synthesized fur evaliiatioii :ti ceiitral nervous system depressants. The compounds were prepared by several procedures.

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8. pubs.acs.org › doi › 101-Phenylcycloalkylamine derivatives. II. Synthesis and ...

   pubs.acs.org › doi › 10

   An expedient synthesis of high specific activity tritium labelled 4‐fluoro‐1‐[1‐(2‐thienyl)]cyclohexylpiperidine ([ 3 H]FTCP), a ligand for further characterization of the phencyclidine/NMDA receptor complex.

9. link.springer.com › referenceworkentry › 10Arylcyclohexamines (Ketamine, Phencyclidine, and Analogues)

   link.springer.com › referenceworkentry › 10

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   Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N -ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo).