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Oct 14, 2021 · Dates. Create: 2005-03-26. Modify: 2024-03-16. Description. 1-phenylcyclohexylamine is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence. It is a Immediate precursors substance.
When the alkylated products are 1 o, 2 o, and 3 o amines, they can be deprotonated with NaOH to produce the neutral amine. When a 3 o amine is alkylated, a quaternary ammonium salt is produced. Alkylation is an efficient method for the synthesis of 3 o and 4 o amines.
Synthesis and antinociception properties of phencyclidine derivatives with modified aromatic or cycloalkyl rings and amino group. Monatshefte für Chemie - Chemical Monthly 2016, 147 (2) , 457-464. https://doi.org/10.1007/s00706-015-1472-1. Dissociative Anesthetics. 2015,,, 697-754. https://doi.org/10.1201/b18962-7
- Asher Kalir, Habib Edery, Zvi Pelah, D. Balderman, Gila Porath
- 1969
Synthesis of PCP from PCA via 1-phenylcyclohexanol (PCOH) The PCOH starting material can be purchased or prepared by reaction of phenyllithium or phenyl grignard with cyclohexanone. This alcohol is then be transformed into the amine by reaction with sodium azide (~90% yield) followed by reduction.
Apr 2, 2013 · The present study describes the synthesis of three substituted 1- (1-phenylcyclohexyl)piperidines, (3-MeO-, 4-MeO- and 3-Me-PCP) and three substituted 1- (1-phenylcyclohexyl)pyrrolidine analogues (3-MeO-, 4-MeO- and 3-Me-PCPy).
- Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt
- 2014
Feb 6, 2010 · N-Phenylcyclohexylamine. Formula: C 12 H 17 N. Molecular weight: 175.2701. IUPAC Standard InChI: InChI=1S/C12H17N/c1-3-7-11 (8-4-1)13-12-9-5-2-6-10-12/h1,3-4,7-8,12-13H,2,5-6,9-10H2. Copy Sheet of paper on top of another sheet. IUPAC Standard InChIKey: TXTHKGMZDDTZFD-UHFFFAOYSA-N.
May 1, 1990 · 1. Highly Influenced. PDF. 3 Excerpts. Synthesis, radiosynthesis, and biological evaluation of fluorinated thienylcyclohexyl piperidine derivatives as potential radiotracers for the NMDA receptor-linked calcium ionophore.