Synthesis of PCP from PCA via 1-phenylcyclohexanol (PCOH) The PCOH starting material can be purchased or prepared by reaction of phenyllithium or phenyl grignard with cyclohexanone. This alcohol is then be transformed into the amine by reaction with sodium azide (~90% yield) followed by reduction.
May 7, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide -based reagents used as accelerators for vulcanization . It is a building block for pharmaceuticals (e.g., mucolytics , analgesics , and bronchodilators ).
4-Phenylcyclohexylamine | C12H17N | CID 29897 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
The nucleus (plural, nuclei) houses the cell’s genetic material, or DNA, and is also the site of synthesis for ribosomes, the cellular machines that assemble proteins. Inside the nucleus, chromatin (DNA wrapped around proteins, described further below) is stored in a gel-like substance called nucleoplasm.
V. H. Maddox, E. F. Godefroi, R. Parcell. Published in Journal of Medicinal… 1 March 1965. Chemistry, Medicine. TLDR. Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants and tested for cataleptoid activity and antitonic extensor properties. Expand.