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thesis of 1-phenylcyclohexylamine. The compound prepared by the alternate route (method F) was identi- cal in all respects with the one obtained prepared from Method F aC6"I NCO - CxCeH5 "2 VI phenylcyclohexene. Recently, Cristol, et ul., re- ported the isolation of the amine as its benzoyl deriva- tive via a modified Ritter reaction.
- 678KB
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5F32 DA05287-02/DA/NIDA NIH HHS/United States. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a motor-toxicity assay. In addition, we determined the binding affinities of the compounds for PCP acceptor sites
- Andrew Thurkauf, Brian De Costa, Shun Ichi Yamaguchi, Mariena V. Mattson, Arthur E. Jacobson, Kenner...
- 1990
Apr 2, 2013 · Drug Testing and Analysis is a specialist journal covering sports doping, recreational drugs, pharmaceuticals, toxico-pathology, forensics, and the environment.
- Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt
- 2014
Mar 26, 2014 · Drug Testing and Analysis is a specialist journal covering sports doping, recreational drugs, pharmaceuticals, toxico-pathology, forensics, and the environment.
- Hamilton Morris, Jason Wallach
- 2014
Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants and tested for cataleptoid activity and antitonic extensor properties. Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants. The compounds were prepared by several procedures. 1-(1-Phenylcyclohexyl)piperidine, the first compound of this type ...
1-Phenylcyclohexylamine (PCA), an analog of phenyclidine (PCP) in which the piperidine ring is replaced by a primary amino group, and its conformationally restricted ...
May 1, 1990 · Several analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, exhibited a greater separation of potencies in the motor toxicity and MES seizure tests than did the parent compound PCA. Thirty-eight analogues of 1-phenylcyclohexylamine (PCA), a phencyclidine (PCP) derivative, were examined for their activities in the mouse maximal electroshock (MES) seizure test and in a ...
