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  2. The plague of Justinian or Justinianic plague (AD 541–549) was an epidemic that afflicted the entire Mediterranean Basin, Europe, and the Near East, severely affecting the Sasanian Empire and the Byzantine Empire, especially Constantinople.

    • 541–549
    • Mediterranean Basin, Europe, Near East
  3. Plague of Justinian, plague pandemic that spread throughout the Mediterranean region and beyond beginning about 541 CE. It is named for Justinian I, who was the Byzantine emperor at that time.

  4. Dec 26, 2014 · During the reign of the emperor Justinian I (527-565 CE), one of the worst outbreaks of the plague took place, claiming the lives of millions of people. The plague arrived in Constantinople in 542 CE...

  5. Dec 3, 2019 · The Justinianic plague—named for Justinian I, the eastern Roman emperor in power during the first outbreak—arose in the sixth century, intermittently recurring throughout Europe and the Middle...

  6. Jun 12, 2020 · The “Justinianic Plague” is the popular name for a pandemic of bubonic plague in the Late Roman or Byzantine Empire, which first appears in our sources in 541 CE. The pandemic reappeared in waves in different regions over the next two hundred years, ending ca. 750 CE.

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  7. Named after the Byzantine Emperor Justinian I, who reigned during its first outbreak, this plague swept across the known world in the mid-6th century, leaving a trail of death and despair in its wake. But what were the origins of this plague? How did it spread so rapidly and widely?

  8. The Plague of Justinian (541–542 CE) was one of the worst plagues in recorded history, arguably bringing two major empires to devastation and affecting numerous societies across Eurasia. The only other known event comparable to its impact was the Black Death of the 14th century.

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