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  2. Apr 28, 2017 · Polygenic inheritance is a system where a trait is controlled by two or more genes and their interactions. Learn how polygenic traits are inherited, such as skin color and height, and how they differ from Mendelian traits.

    • Polygenic Inheritance Definition
    • Characteristics of Polygenic Inheritance
    • Analysis of Polygenic Traits
    • Difference Between Polygenic Traits and Oligogenic Traits
    • Segmentation of Polygenic Variability
    • Effect of Environment on Polygenic Inheritance
    • Why Is Polygenic Inheritance Important?
    • References

    What is polygenic inheritance? Polygenic inheritance, in simple terms, implies a character or phenotypic trait, which is regulated by more than one gene. In biology, it refers to the quantitative inheritance wherein two or more independent genes additively affect a single phenotypic trait. In a way, polygenic inheritance is a multiple factor inheri...

    A gene that employs a minor effect on a phenotype along with other genes is referred to as polygenes.
    The effect of an individual gene is too minor and often remains undetected
    Numerous genes exert an equal effect.
    Individually, each allele contributes to the result in a cumulative or additive manner

    The pioneering work to understand the quantitative characters in terms of Mendelian genetics was carried out by Sir Ronald Aylmer (R.A.) Fisher in 1918. As we are aware that polygenic inheritance is a quantitative inheritance. Hence, it becomes important to understand the approaches or basis to differentiate between quantitative and qualitative inh...

    Oligogenic traitsare controlled by a limited number of genes whereas polygenic traits are controlled by a number of genes. The difference between polygenic trait and oligogenic traits are enlisted in the table below. Table 1: Polygenic traits vs Oligogenic traits

    Variance is used to segregate the polygenic variation or variability present in a genetic population. The variation in polygenic inheritance is of three types. They are: 1. Phenotypic It is the observable variability and most often is the total variability which may include environmental as well as genotypic variations. It is expressed as the pheno...

    Polygenes are highly influenced by environmental factors. Basically, the genotype of an individual sets the range of the quantitative trait while the phenotype of the trait is eventually an outcome of the environmental factors. Different environmental conditions regulate the gene function resulting in varying gene function. Accordingly, under diffe...

    Polygenes are responsible for the population variance and have evolutionary significance. These polygenic variations or changes (polygenesis) are responsible for the evolution of species. This is also known as the theory of polygeny for evolution. The variations are according to the specific requirement and needs of the individual or species. These...

    Carter C. O. (1969). Polygenic inheritance and common diseases. Lancet (London, England), 1(7608), 1252–1256. https://doi.org/10.1016/s0140-6736(69)92130-8
    Carter C. O. (1977). Principles of polygenic inheritance. Birth defects original article series, 13(3A), 69–74.
    Khoury, M. J., Janssens, A. C., & Ransohoff, D. F. (2013). How can polygenic inheritance be used in population screening for common diseases?. Genetics in medicine : official journal of the America...
    Lange K. (1997). An approximate model of polygenic inheritance. Genetics, 147(3), 1423–1430.
  3. Learn how complex traits like height are influenced by multiple genes and environmental factors. Explore examples of polygenic inheritance and how it differs from Mendelian genetics.

  4. 8.4: Polygenic Inheritance. Page ID. Natasha Ramroop Singh. Thompson Rivers University. Continuous Variation. Most of the phenotypic traits commonly used in introductory genetics are qualitative. This means the phenotype exists in only two (or possibly a few more) discrete, alternative forms, such as purple or white flowers, or red or white eyes.

  5. Jul 13, 2018 · Polygenic inheritance is the inheritance of traits that are influenced by several genes, such as skin color, eye color, and height. Learn how polygenic traits are determined by additive and incomplete dominance, and how they have a bell-shaped distribution in a population.

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  6. Jul 31, 2022 · How, then, is height inherited? Height and other similar features are controlled not just by one gene, but rather, by multiple (often many) genes that each make a small contribution to the overall outcome. This inheritance pattern is called polygenic inheritance (poly– = many).

  7. Dec 14, 2021 · In this article, we’ll examine how complex traits such as height are inherited. We'll also see how factors like genetic background and environment can affect the phenotype (observable features) produced by a particular genotype (set of gene variants, or alleles).

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