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  1. The polymerase chain reaction (PCR) is a method widely used to make millions to billions of copies of a specific DNA sample rapidly, allowing scientists to amplify a very small sample of DNA (or a part of it) sufficiently to enable detailed study.

    • Taq Polymerase

      Taq polymerase is a thermostable DNA polymerase I named...

    • Thermal Cycler

      A Modern PCR Machine. The thermal cycler (also known as a...

    • Primers

      The polymerase chain reaction (PCR) uses a pair of custom...

    • Quantitative PCR

      A real-time polymerase chain reaction (real-time PCR, or...

    • Kary Mullis

      Kary Banks Mullis (December 28, 1944 – August 7, 2019) was...

  2. A real-time polymerase chain reaction (real-time PCR, or qPCR when used quantitatively) is a laboratory technique of molecular biology based on the polymerase chain reaction (PCR). It monitors the amplification of a targeted DNA molecule during the PCR (i.e., in real time), not at its end, as in conventional PCR.

  3. Jul 28, 2024 · The polymerase chain reaction enables investigators to obtain the large quantities of DNA that are required for various experiments and procedures in molecular biology, forensic analysis, evolutionary biology, and medical diagnostics.

    • The Editors of Encyclopaedia Britannica
  4. Polymerase chain reaction (PCR) enables researchers to produce millions of copies of a specific DNA sequence in approximately two hours. This automated process bypasses the need to use bacteria for amplifying DNA.

  5. Jan 30, 2017 · polymerase chain reaction (PCR) A biochemical process that repeatedly copies a particular sequence of DNA. A related, but somewhat different technique, copies genes expressed by the DNA in a cell. This technique is called reverse transcriptase PCR.

  6. Jul 26, 2017 · The polymerase chain reaction or PCR is used to make multiple copies of a specific sequence of DNA called the target DNA. The DNA is collected from a sample of interest – for example, someone’s hair follicle, material from a crime scene, an ancient bone, a plant seed or cancerous tissue.

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  8. Aug 17, 2020 · What is PCR? Sometimes called "molecular photocopying," the polymerase chain reaction (PCR) is a fast and inexpensive technique used to "amplify" - copy - small segments of DNA.

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