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  1. Nov 16, 2023 · Initial dose: 1 mg orally 2 or 3 times a day. Maintenance dose: 1 to 20 mg orally per day in divided doses. Comments: Titrate slowly as determined by blood pressure response. Therapeutic dosages usually range from 6 to 15 mg per day in divided doses.

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  2. The prazosin dose ranged from 1 to 16 mg/d. Results were mixed for the 4 RCTs: 3 reported significant improvement in the number of nightmares, and 1 found no reduction in the number of nightmares. Reduced nightmare severity with use of prazosin was consistently reported in the open-label trials, retrospective chart reviews, and single case reports.

    • Simon Kung, Zelde Espinel, Maria I. Lapid
    • 10.1016/j.mayocp.2012.05.015
    • 2012
    • Mayo Clin Proc. 2012 Sep; 87(9): 890-900.
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  4. PTSD-Related Nightmares & Sleep Disruption (Off-label) Initial: 1 mg PO qHS. Maintenance: 1 mg PO qHS initially; may increase dose to 2 mg qHS; adjust dose based on response and tolerability...

    • prazosin for nightmares dosage chart1
    • prazosin for nightmares dosage chart2
    • prazosin for nightmares dosage chart3
    • prazosin for nightmares dosage chart4
    • prazosin for nightmares dosage chart5
  5. Dec 17, 2022 · Fact checked by Nick Blackmer. Print. Minipress (prazosin), a drug commonly used to treat high blood pressure and urinary retention, has been shown in some studies to be safe and effective in managing nightmares and sleep disturbances in people with post-traumatic stress disorder (PTSD).

  6. Mar 1, 2024 · For oral dosage form (capsules): For high blood pressure: Adults—At first, 1 milligram (mg) 2 or 3 times a day. Your doctor will slowly increase your dose as needed. However, the dose is usually not more than 20 mg per day. Children—Use and dose must be determined by your doctor.

  7. Prazosin is well tolerated, with doses ranging from 1 to 16 mg/d. Most studies were from a common Veterans Administration research group, and 2 newer studies reported less impressive results.

  8. Aug 17, 2023 · Prazosin has therapeutic use for benign prostatic hypertrophy (BPH), post-traumatic stress disorder (PTSD) associated nightmares, Raynaud phenomenon, pheochromocytoma, and scorpion envenomation. Prazosin was the first alpha antagonist used for BPH.

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