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Pregabalin and gabapentin. Pregabalin (Lyrica) is effective for treating GAD. It acts on the voltage-dependent calcium channel to decrease the release of neurotransmitters such as glutamate, norepinephrine and substance P.
Dec 25, 2008 · Pregabalin.svg. Size of this PNG preview of this SVG file: 239 × 113 pixels. Other resolutions: 320 × 151 pixels | 640 × 303 pixels | 1,024 × 484 pixels | 1,280 × 605 pixels | 2,560 × 1,210 pixels. Original file (SVG file, nominally 239 × 113 pixels, file size: 9 KB)
Dec 19, 2018 · 11 DESCRIPTION Pregabalin is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid.The molecular formula is C 8 H 17 NO 2 and the molecular weight is 159.23. The chemical structure of pregabalin is: Pregabalin is a white to off-white, crystalline solid with a pK a1 of 4.2 and a pK a2 of 10.6.
4-Methylpregabalin. 4-Methylpregabalin is a drug developed by Pfizer and related to pregabalin, which similarly acts as an analgesic with effectiveness against difficult to treat "atypical" pain syndromes such as neuropathic pain. The effectiveness of pregabalin and its older relative gabapentin against pain syndromes of this kind (which tend ...
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Pregabalin' je antikonvulsant koji se koristi za tretiranje neuropatičkog bola, kao dodatna terapija za parcijalne konvulzije, i za generalizovani anksiozni poremećaj. Ovaj lek je razvijen da bude potentniji naslednik gabapentina .
Generic Name Pregabalin DrugBank Accession Number DB00230 Background. Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. 13 It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. 20 Although as per the FDA Label the mechanism of action has not been definitively characterized, there is ...
