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  1. These revised recommendations by the Advisory Committee on Immunization Practices concerning prevention of plague update previous recommendations (MMWR 1982;31:301-4). This report includes information and recommendations on vaccination, public health practices, and medical treatment to prevent plague among humans. INTRODUCTION

  2. Pneumonic plague – or lung-based plague – is the most virulent and least common form of plague. Typically, it is caused by spread to the lungs from advanced bubonic plague. However, a person with secondary pneumonic plague may form aerosolized infective droplets and transmit plague to other humans. This is usually fatal.

  3. May 15, 2024 · Plague is a potentially life-threatening disease caused by the bacterium, Yersinia pestis. Plague occurs naturally in areas of the western United States, where it circulates among wild rodents and other animals. Plague can be cured with antibiotics, but treatment must be given quickly.

  4. Amongst the newer generation of antibiotics, gentamicin and doxycycline have proven effective in monotherapeutic treatment of plague. [6] [29] Guidelines on treatment and prophylaxis of plague were published by the Centers for Disease Control and Prevention in 2021. [7]

  5. Before the advent of antibiotics, treatment of plague . primarily consisted of supportive care, and fatality rates were high, between 66% and 93%, for all clinical forms (3, 13). The development of sulfonamide antibiotics in the 1930s revolutionized the treatment of plague. Patients with pneumonic plague, previously considered incurable, were able

  6. Aug 7, 2023 · Plague is caused by Yersinia pestis, perhaps one of the most important bacterial pathogens in human history. It occurs in epidemics and pandemics with extremely high mortality when untreated. Prevention and rapid treatment are essential to avoid large outbreaks and the death of those infected with this pathogen.

  7. Apr 20, 2023 · Plague usually can be treated with antibiotics. If not treated, the illness is often deadly. Plague is considered a potential bioweapon. The U.S. government has plans and treatments in place if the disease is used as a weapon.

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