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- www.ncbi.nlm.nih.gov
- › …
- › J Thorac Dis
- › v.12(Suppl 1); 2020 Feb
Nov 20, 2019 · Most importantly, PCT helps in guiding antibiotic use in patients with respiratory infection and sepsis by limiting initiation and by shortening treatment duration. To date, PCT is the best studied biomarker regarding antibiotic stewardship.
Apr 23, 2023 · Procalcitonin (PCT) serum levels have been shown to increase 6 to 12 hours following initial bacterial infections and increase steadily in the two to four hours following the onset of sepsis.
Apr 1, 2020 · Initial evaluation of patients with suspected sepsis includes basic laboratory tests, cultures, imaging studies as indicated, and sepsis biomarkers such as procalcitonin and lactate levels....
- www.ncbi.nlm.nih.gov
- › …
- › J Intensive Care
- › v.5; 2017
Aug 3, 2017 · Procalcitonin (PCT), a member of the calcitonin super family could be a critical tool for the diagnosis of sepsis. But to distinguish between bacterial versus viral infections, procalcitonin alone may not be effective.
Jun 9, 2024 · A procalcitonin test measures the risk of developing a potentially deadly bacterial infection called sepsis. Sepsis occurs when the body overreacts to a bacterial infection by releasing chemicals that can cause damaging inflammation.
May 4, 2023 · Procalcitonin (PCT), a peptide precursor of the hormone calcitonin, is a biomarker whose serum concentrations are elevated in response to systemic inflammation caused by bacterial infection and sepsis.
Feb 1, 2013 · patients with a high procalcitonin concentration are more likely to have sepsis than are patients with a low procalcitonin concentration. To provide more precise information about the reliability of the test, we suggest calculating likelihood ratios based on multiple cutoffs.
Role of procalcitonin use in the management of sepsis. Abstract. Important aspects of sepsis management include early diagnosis as well as timely and specific treatment in the first few hours of triage. However, diagnosis and differentiation from non-infectious causes often cause uncertainties and potential time delays.
High initial procalcitonin levels are a sensitive marker of bacterial infection, and the degree of procalcitonin elevation may determine which patients are at greater risk for adverse outcomes (mortality or ICU admission).
Procalcitonin is the propeptide of calcitonin, a 116-peptide molecule with a molecular weight of 13 kDa. Procalcitonin has been studied as a sepsis biomarker, to help with diagnosing/ ruling out sepsis and to guide the initiation and cessation of antibiotics.
