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Treatment of P. aeruginosa infections is challenging because of the limited choices of antibiotics and the emergent resistance of the pathogen. The present review aims at addressing the management of P. aeruginosa infections and highlighting the novel antibiotics that show a future promising role.
Feb 16, 2023 · The concept of “difficult-to-treat resistant” (DTR) Pseudomonas aeruginosa, proposed in 2018, is based on the not so rare instance of a strain resistant to all of the following antibiotics: ceftazidime, cefepime, piperacillin-tazobactam, aztreonam, imipenem-cilastatin, meropenem, ciprofloxacin, and levofloxacin.
Pseudomonas aeruginosa infections are generally treated with antibiotics. Unfortunately, in people exposed to healthcare settings like hospitals or nursing homes, Pseudomonas aeruginosa infections are becoming more difficult to treat because of increasing antibiotic resistance.
Aug 8, 2023 · Pseudomonas aeruginosa is a gram-negative, aerobic, non-spore forming rod that is capable of causing a variety of infections in both immunocompetent and immunocompromised hosts. Its predilection to cause infections among immunocompromised hosts, extreme versatility, antibiotic resistance, and a wide range of dynamic defenses makes it an ...
Mar 3, 2023 · Pseudomonas infection can be treated with a combination of an antipseudomonal beta-lactam (eg, penicillin or cephalosporin) and an aminoglycoside. Carbapenems (eg, imipenem, meropenem) with antipseudomonal quinolones may be used in conjunction with an aminoglycoside.
Aug 25, 2023 · The general principles of antimicrobial treatment of infections caused by P. aeruginosa, including antibiotic options and decisions on combination therapy, are discussed in detail elsewhere. (See "Principles of antimicrobial therapy of Pseudomonas aeruginosa infections" .)
Jan 27, 2023 · Consideration of this organism is important because it causes severe and often fatal hospital-acquired infections, especially in immunocompromised hosts. Selection of antibiotic treatment for P. aeruginosa is complicated because it is often antibiotic resistant.
