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Nov 22, 2021 · Fluoroquinolones can cause mild side effects including nausea, diarrhea, and vomiting. In rare cases, these medications can cause more serious side effects. This can involve the tendons, muscles, heart, and nerves. These are signs of fluoroquinolone toxicity. Some of these serious side effects can occur as a result of taking fluoroquinolones.
Oct 1, 2021 · Tendinopathy. Fluoroquinolones are associated with a two- to fourfold increased risk of acute tendinopathy (defined as pain or reduced function without rupture) and tendon rupture.3 The incidence of this adverse effect may be up to 2% in patients aged 65 years and above, compared with a background tendon rupture rate of approximately 0.9% in the general population.4,5
- Diva Baggio, Michelle R Ananda-Rajah
- 2021
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May 22, 2023 · Quinolones are a class of broad-spectrum antibiotics used in the management and treatment of many different bacterial infections. This activity reviews the indications, contraindications, mechanism of action, adverse events, and other critical elements of quinolone therapy in the clinical setting pertinent for healthcare team members in managing the care of patients with bacterial infections ...
- Amanda Yan, Emily E. Bryant
- 2023/05/22
Oct 1, 2019 · Despite these increasing concerns of quinolone resistance and toxicity, the use of this class of antibiotics still remains high as it is effective for serious infections.99 The development of novel quinolone or quinolone-like agents with improved properties is still desirable, particularly if these new agents are only used to treat appropriate ...
- 10.1039/c9md00120d
- 2019/10/10
- Medchemcomm. 2019 Oct 1; 10(10): 1719-1739.
Mar 21, 2018 · When antibiotics turn toxic. Commonly prescribed drugs called fluoroquinolones cause rare, disabling side effects. Researchers are struggling to work out why. In 2014, Miriam van Staveren went on ...
- Jo Marchant
- 2018
In Wikidata. Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. [1] They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry, specifically poultry production.
Feb 21, 2024 · INTRODUCTION. Fluoroquinolones are highly effective antibiotics with many advantageous pharmacokinetic properties including high oral bioavailability, large volume of distribution, and broad-spectrum antimicrobial activity. With widespread use, antimicrobial resistance to fluoroquinolones has grown. In addition, fluoroquinolones carry risk of ...
