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Raphe (/ ˈ r eɪ f i / RAY-fee; from Ancient Greek: ῥαφή, romanized: rhaphḗ, lit. 'seam'; pl.: raphae or raphes) has several different meanings in science. In botany and planktology, it is commonly used when describing a seam or ridge on diatoms or seeds. In animal anatomy, it is used to describe a ridged union of continuous biological ...
RAPHE meaning: 1. a place or line where two halves of an organ in the body join 2. a place or line where two…. Learn more.
Aug 14, 2019 · The dorsal raphe nucleus (DRN) is an important source of neuromodulators and has been implicated in a wide variety of behavioral and neurological disorders. The DRN is subdivided into distinct anatomical subregions comprised of multiple cell types, and its complex cellular organization has impeded efforts to investigate the distinct circuit and ...
noun. A seamlike line or ridge between two similar parts of a body organ, as in the scrotum. The portion of the funiculus that is united to the ovule wall, commonly visible as a line or ridge on the seed coat. A groove in the frustule of some diatoms.
RAPHE definition: 1. a place or line where two halves of an organ in the body join 2. a place or line where two…. Learn more.
The raphe nucleus is responsible for most of the serotonergic cortical and striatal innervation. Tryptophan, the precursor of serotonin, is first converted into 5-hydroxytryptophan, by the rate-limiting step catalyzed by tryptophan hydroxylase, and promptly transformed into serotonin by AAD.
The raphe neurons are located in the central tegmentum of the midbrain and the upper pons. They are serotonergic neurons projecting to wide areas of the cerebral cortex and the striatum. In PD, raphe neurons are also involved but to a lesser degree compared to the substantia nigra.
