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The raphe nuclei ( Greek: ῥαφή, "seam") [1] are a moderate-size cluster of nuclei found in the brain stem. They have 5-HT1 receptors which are coupled with Gi/Go-protein -inhibiting adenyl cyclase. They function as autoreceptors in the brain and decrease the release of serotonin.
- nuclei raphe
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May 1, 2023 · The raphe nuclei are positioned midline in the brainstem throughout the midbrain, pons, and medulla. These nuclei contain primarily serotonergic neurons, which release serotonin (5-hydroxytryptamine) with autocrine and paracrine effects, as well as synaptic connections.
- Emily P. Walker, Prasanna Tadi
- 2023/05/01
- 2019
Jul 24, 2023 · The raphe nuclei are located midline throughout the brainstem within the pons, midbrain, and medulla. The majority of neurons located in the raphe nuclei are serotonergic. The more rostral raphe nuclei appear to be important in various bodily functions, including pain sensation and mood regulation.
- Joseph H. Arguinchona, Prasanna Tadi
- Asram Medical College, Eluru, India
- 2020
- 2023/07/24
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Jul 24, 2023 · The raphe nuclei form a central ridge of the reticular formation and play an important role in mood regulation and arousal through neurotransmission via serotonin and projections to the limbic regions. The medial column of the gigantocellular reticular nuclei is composed of larger neurons and coordinates motor movements.
- Sarah A. Mangold, Joe M Das
- 2023/07/24
- 2021
May 25, 2022 · The raphe nuclei comprise nearly all of 5-hydroxytryptaminergic (5-HTergic) neurons in the brain and are widely acknowledged to participate in the modulation of neural excitability.
May 1, 2023 · The raphe nuclei are positioned midline in the brainstem throughout the midbrain, pons, and medulla. These nuclei contain primarily serotonergic neurons, which release serotonin (5-hydroxytryptamine) with autocrine and paracrine effects, as well as synaptic connections.
Jan 11, 2016 · Abstract. The serotonergic raphe nuclei are involved in regulating brain states over timescales of minutes and hours. We examined more rapid effects of raphe activation on two classes of principal ...
