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The raphe nuclei ( Greek: ῥαφή, "seam") [1] are a moderate-size cluster of nuclei found in the brain stem. They have 5-HT1 receptors which are coupled with Gi/Go-protein -inhibiting adenyl cyclase. They function as autoreceptors in the brain and decrease the release of serotonin.
- nuclei raphe
- nlx_anat_20090205
May 1, 2023 · The raphe nuclei are positioned midline in the brainstem throughout the midbrain, pons, and medulla. These nuclei contain primarily serotonergic neurons, which release serotonin (5-hydroxytryptamine) with autocrine and paracrine effects, as well as synaptic connections. Serotonin generation comes from L-tryptophan via a two-step process catalyzed by tryptophan hydroxylase and L-aromatic amino ...
- Emily P. Walker, Prasanna Tadi
- 2023/05/01
- 2019
Jul 24, 2023 · The raphe nuclei are located midline throughout the brainstem within the pons, midbrain, and medulla. The majority of neurons located in the raphe nuclei are serotonergic. The more rostral raphe nuclei appear to be important in various bodily functions, including pain sensation and mood regulation.
- Joseph H. Arguinchona, Prasanna Tadi
- Asram Medical College, Eluru, India
- 2020
- 2023/07/24
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Jul 24, 2023 · The raphe nuclei form a central ridge of the reticular formation and play an important role in mood regulation and arousal through neurotransmission via serotonin and projections to the limbic regions. The medial column of the gigantocellular reticular nuclei is composed of larger neurons and coordinates motor movements.
- Sarah A. Mangold, Joe M Das
- 2023/07/24
- 2021
Mar 2, 2021 · The raphe nuclei are neuronal aggregates along the brainstem that produce and release serotonin, a neurotransmitter involved in many functions. Learn about their anatomy, distribution, and roles in sleep, pain, mood, and behavior.
May 1, 2023 · The raphe nuclei are positioned midline in the brainstem throughout the midbrain, pons, and medulla. These nuclei contain primarily serotonergic neurons, which release serotonin (5-hydroxytryptamine) with autocrine and paracrine effects, as well as synaptic connections. Serotonin generation comes from L-tryptophan via a two-step process ...
Learn about the raphe nuclei, a group of serotonergic neurons in the brainstem that project to various brain regions and spinal cord. Find out their functions, distribution, and involvement in diseases such as Parkinson's and aging.
