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  1. en.wikipedia.org › wiki › Raphe_nucleiRaphe nuclei - Wikipedia

    The raphe nuclei ( Greek: ῥαφή, "seam") [1] are a moderate-size cluster of nuclei found in the brain stem. They have 5-HT1 receptors which are coupled with Gi/Go-protein -inhibiting adenyl cyclase. They function as autoreceptors in the brain and decrease the release of serotonin.

  2. May 1, 2023 · Recent Activity. See more... The raphe nuclei are positioned midline in the brainstem throughout the midbrain, pons, and medulla. These nuclei contain primarily serotonergic neurons, which release serotonin (5-hydroxytryptamine) with autocrine and paracrine effects, as well as synaptic connections.

    • Emily P. Walker, Prasanna Tadi
    • 2023/05/01
    • 2019
  3. May 25, 2022 · Numerous researches have shown that the raphe nuclei 5-hydroxytryptamine (5-HT)ergic system plays an important role not only in many physiological functions such as mood regulation, but also in ...

  4. Aug 14, 2019 · The dorsal raphe nucleus (DRN) is a major source of neuromodulators in the central nervous system, and is the largest of the serotonergic nuclei, containing approximately a third of all serotonergic neurons (5-HT neurons) in the brain ( Hornung, 2010 ). DRN 5-HT neurons send highly divergent projections that target many functionally distinct ...

    • Kee Wui Huang, Nicole E Ochandarena, Adrienne C Philson, Minsuk Hyun, Jaclyn E Birnbaum, Marcelo Cic...
    • 2019
  5. Jan 11, 2016 · The serotonergic raphe nuclei modulate neuronal function typically over minutes or hours. The authors report that raphe nuclei affect odor responses in output neurons of the olfactory bulb at sub ...

    • Vikrant Kapoor, Allison C Provost, Prateek Agarwal, Venkatesh N Murthy
    • 2016
  6. Definition. The raphe nuclei are a moderate-size cluster of nuclei found in the brain stem. Their main function is to release serotonin to the rest of the brain. The raphe nuclei are traditionally considered to be the medial portion of the reticular formation, and appear as a ridge of cells in the center and most medial portion of the brain ...

  7. The raphe nuclei is a cluster of neurons that are housed in the pons and medulla within the hindbrain . Functionally, it is the primary site of serotonin production [ 5 ]. Serotonin is an essential neurotransmitter of the central nervous system that is found throughout brain regions that play a vital role in regulating aspects of eating, sleep ...

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