Two-term Republican Pat Toomey was re-elected in 2016 with 48.8% of the vote. On October 5, 2020, Toomey announced that he will retire at the end of his term. Pennsylvania Lieutenant Governor John Fetterman is running in the Democratic primary, as is state representative Malcolm Kenyatta.
Trump won Missouri again by a 15.4% margin; this was somewhat worse than his 18.5% margin in 2016. Biden performed three points better than Hillary Clinton in 2016 . Prior to the election, all 12 news organizations considered this a state Trump would win, or a likely red state .