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  2. 5 days ago · Background The factors contributing to the accelerated convergent evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are not fully understood. Unraveling the contribution of viral replication in immunocompromised patients is important for the early detection of novel mutations and developing approaches to limit COVID-19. Methods We deep sequenced SARS-CoV-2 RNA from 192 ...

  3. 4 days ago · Throughout the COVID-19 pandemic, SARS-CoV-2 variants have been designated as variants of concern (VOCs) and variants of interest (VOIs) on the basis of their potential to replace...

  4. 1 day ago · Neutralizing antibodies targeting the spike (S) protein of SARS-CoV-2, elicited either by natural infection or vaccination, are crucial for protection against the virus. Nonetheless, the emergence of viral escape mutants presents ongoing challenges by contributing to breakthrough infections. To define the evolution trajectory of SARS-CoV-2 within the immune population, we co-incubated ...

  5. 1 day ago · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a global threat, causing severe respiratory illness and fatalities. 1,2 Phylogenetically related to the 2003 SARS-CoV epidemic, 3 ...

  6. 5 days ago · The researchers wanted to follow RNA replication errors because they are crucial for understanding how the virus evolves, how it changes and adapts as it spreads in the human population, but current methods lacked the precision to detect rare new SARS-CoV-2 mutations, particularly in samples with a low number of viruses, such as those from ...

  7. 3 days ago · Latest Research and Reviews. High SARS-CoV-2 incidence and asymptomatic fraction during Delta and Omicron BA.1 waves in The Gambia. Many low- and middle-income countries, including The...

  8. 2 days ago · Although the emergency has ended, the pandemic has not, and COVID-19 is currently causing ∼ 1,000 deaths per week in the United States. 1 If this is the endemic pace of mortality from SARS-CoV-2, it will add to 12,000–52,000 deaths from influenza per year, more than doubling the total of deaths caused by respiratory viruses. 2 SARS-CoV-2 ...

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